Mechanisms and therapeutic potential of chinonin in nervous system diseases.

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-07-08 DOI:10.1080/10286020.2024.2371040

Zhang Hui, Wang Lai-Fa, Wang Xue-Qin, Deng Ling, He Bin-Sheng, Jian-Ming Li

引用次数: 0

Abstract

The flavonoid compound chinonin is one of the main active components of Rhizoma anemarrhena with multiple activities, including anti-inflammatory and antioxidant properties, protection of mitochondrial function and regulation of immunity. In this paper, we reviewed recent research progress on the protective effect of chinonin on brain injury in neurological diseases. "Chinonin" OR "Mangiferin" AND "Nervous system diseases" OR "Neuroprotection" was used as the terms for search in PumMed. After discarding duplicated and irrelevant articles, a total of 23 articles relevant to chinonin published between 2012 and 2023 were identified in our study.

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奇诺宁在神经系统疾病中的作用机制和治疗潜力。

黄酮类化合物chinonin是金莲花的主要活性成分之一，具有多种活性，包括抗炎、抗氧化、保护线粒体功能和调节免疫力。在本文中，我们综述了近期有关奇诺宁对神经系统疾病中脑损伤的保护作用的研究进展。在 PumMed 中使用 "奇诺宁 "或 "芒果苷 "和 "神经系统疾病 "或 "神经保护 "作为检索词。在剔除重复和不相关的文章后，我们的研究共发现了 23 篇 2012 年至 2023 年间发表的与芒果苷相关的文章。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.