Risk factors of cerebral aneurysms rupture in an Indonesian population.

IF 1.7 4区医学 Q3 CLINICAL NEUROLOGY

Neurological Research Pub Date : 2024-11-01 Epub Date: 2024-07-06 DOI:10.1080/01616412.2024.2376308

Beny Rilianto, Ricky Gusanto Kurniawan, Bambang Tri Prasetyo, Pratiwi Raissa Windiani, Kelvin Theandro Gotama, Muhammad Kusdiansah, Abrar Arham

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引用次数: 0

Abstract

Background: The demographic, clinical, and angiographic features of ruptured aneurysms compared to unruptured cerebral aneurysms in Indonesia are still limited. This study aims to determine risk factors for rupture according to clinical patterns and morphological features in the Indonesian population.

Method: We retrospectively reviewed all cerebral aneurysm registries at the largest comprehensive stroke center in Indonesia from January 2019 to January 2022. We compared demographic and vascular risk factors as well as angiographic features between patients with ruptured and unruptured aneurysms with univariate and multivariate analyses.

Results: Of 275 patients, 231 (84%) had ruptured cerebral aneurysms. We found a significant difference between the ruptured and unruptured groups in variables such as age, hypertension, dyslipidemia, smoking, location, and type of aneurysm. It was found that only the anterior circulation site (OR 4.91, 95% CI 1.47-16.48; p < 0.01) and saccular type (OR 5.45, 95% CI 1.42-20.93; p = 0.01) were significantly linked to ruptured aneurysms.

Conclusion: Our findings revealed that anterior location and saccular type were substantially linked with ruptured aneurysms in the Indonesian population.

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印度尼西亚人口中脑动脉瘤破裂的风险因素。

背景：在印度尼西亚，与未破裂的脑动脉瘤相比，破裂动脉瘤的人口统计学、临床和血管造影特征仍然有限。本研究旨在根据印尼人的临床模式和形态特征确定动脉瘤破裂的风险因素：我们回顾性审查了印度尼西亚最大的综合卒中中心从 2019 年 1 月至 2022 年 1 月的所有脑动脉瘤登记。我们通过单变量和多变量分析比较了动脉瘤破裂和未破裂患者的人口统计学、血管风险因素以及血管造影特征：在275名患者中，231人（84%）患有破裂的脑动脉瘤。我们发现破裂组和未破裂组在年龄、高血压、血脂异常、吸烟、位置和动脉瘤类型等变量上存在明显差异。研究发现，只有前循环部位（OR 4.91，95% CI 1.47-16.48；P P = 0.01）与动脉瘤破裂有显著关联：我们的研究结果表明，在印度尼西亚人群中，前循环部位和囊状类型与动脉瘤破裂密切相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.