The Progress and Prospect of calcium peroxide nanoparticles in antibacterial activity

Abstract

This review provides a comprehensive overview of the advancements and potential applications of calcium peroxide nanoparticles (CaO₂ NPs) in combating bacterial infections. With the rise of antibiotic resistance posing a significant global health threat, alternative antibacterial agents like CaO₂ NPs have garnered increasing attention. The review begins by discussing the synthesis and functionalization of CaO₂ NPs, highlighting recent developments in nanoparticle engineering techniques. Subsequently, it explores the intricate antibacterial mechanisms of CaO₂ NPs, emphasizing their ability to generate reactive oxygen species and disrupt bacterial biofilms. Evaluation of CaO₂ NPs' antibacterial efficacy against a broad spectrum of pathogens, coupled with discussions on potential applications in various fields including biomedical and environmental remediation, underscores their promising role as effective antibacterial agents. The review also addresses challenges such as nanoparticle stability and biocompatibility, and proposes future research directions to fully exploit the therapeutic potential of CaO₂ NPs. Overall, this review consolidates current knowledge on CaO₂ NPs and advocates for their continued exploration in combating bacterial infections.