Comment on “Unlocking the therapeutic potential of microalgal astaxanthin a super antioxidant in oral cancer and associated ailments”

Oral Oncology Reports Pub Date : 2024-07-02 DOI:10.1016/j.oor.2024.100571

Antonyraj Matharasi Perianaika Anahas, Ganapathy Dhanraj

{"title":"Comment on “Unlocking the therapeutic potential of microalgal astaxanthin a super antioxidant in oral cancer and associated ailments”","authors":"Antonyraj Matharasi Perianaika Anahas, Ganapathy Dhanraj","doi":"10.1016/j.oor.2024.100571","DOIUrl":null,"url":null,"abstract":"<div><p>Oral cancer treatment potentially advances with the application of C-phycocyanin (C-PC), a powerful antioxidant produced by cyanobacteria. By triggering mechanisms that impair the metabolism of mitochondria and cause cancer cells to initiate apoptosis, this pigment demonstrates potent apoptotic-inducing potentials. Innovative application for C-PC includes integrating it with fibrous scaffolds for long-term release, stimulating tissue regeneration, and lowering inflammation and oxidative damage after surgery. Surgical implants with C-PC, such stents and sutures, provide focused therapy at the locations of oral cancer. In order to enhance the therapeutic uses of C-PC in oral cancer, further studies may investigate genetically modified microalgae. Validating these therapeutic effects and advancing cyanobacterial pigment-based drugs into clinical applications demand further studies.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004175/pdfft?md5=b86cc38af07f9988a9c4308f83abc51e&pid=1-s2.0-S2772906024004175-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772906024004175","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Oral cancer treatment potentially advances with the application of C-phycocyanin (C-PC), a powerful antioxidant produced by cyanobacteria. By triggering mechanisms that impair the metabolism of mitochondria and cause cancer cells to initiate apoptosis, this pigment demonstrates potent apoptotic-inducing potentials. Innovative application for C-PC includes integrating it with fibrous scaffolds for long-term release, stimulating tissue regeneration, and lowering inflammation and oxidative damage after surgery. Surgical implants with C-PC, such stents and sutures, provide focused therapy at the locations of oral cancer. In order to enhance the therapeutic uses of C-PC in oral cancer, further studies may investigate genetically modified microalgae. Validating these therapeutic effects and advancing cyanobacterial pigment-based drugs into clinical applications demand further studies.

查看原文本刊更多论文

关于 "挖掘微藻虾青素这种超级抗氧化剂对口腔癌及相关疾病的治疗潜力 "的评论

蓝藻产生的一种强力抗氧化剂--C-花青素（C-PC）的应用有可能推进口腔癌的治疗。这种色素通过触发损害线粒体新陈代谢的机制，导致癌细胞启动凋亡，具有强大的凋亡诱导潜能。C-PC 的创新应用包括将其与纤维支架整合以实现长期释放、刺激组织再生以及降低术后炎症和氧化损伤。含有 C-PC 的外科植入物（如支架和缝合线）可对口腔癌的发病部位进行集中治疗。为了加强氯化石蜡对口腔癌的治疗作用，进一步的研究可能会对转基因微藻进行调查。验证这些治疗效果并将蓝藻色素药物推向临床应用还需要进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Oral Oncology Reports

CiteScore

0.20

自引率

0.00%

发文量