Superb microvascular imaging (SMI) and elastosonography in thyroid nodule: diagnostic value in a real-time cohort.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI:10.1007/s40477-024-00898-5

Davide Negroni, Gaetano Maddalena, Romina Bono, Flavia Abruzzese, Sara Cesano, Patrizio Conte, Chiara Airoldi, Alessandro Carriero

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引用次数: 0

Abstract

Purpose: In clinical practice, thyroid nodules are classified according to TI-RADS by B-mode and color-flow Doppler study. The aim of the study is to evaluate the possible added value of Superb microvascular imaging (SMI) and elastosonography in the stratification of malignancy risk of thyroid nodules.

Methods: All patients with thyroid nodules who were candidates for needle aspiration were enrolled. Experienced operators performed a standard examination with TI-RADS calculation, followed by SMI and elastosonography on the nodules. The needle aspiration outcome was used as the gold standard. Statistical analysis calculated the ROC curves of the techniques applied individually and serially.

Results: In this prospective study, we analysed 260 nodules, found in 251 patients (mean age 58.6 yo ± 14). 11.2% were TI-RADS 1, 18.9% TI-RADS 2, 41.1% TI-RADS 3, 28.1% TI-RADS 4, and 0.8% TI-RADS 5. The SMI technique showed an AUC of 0.57 (95% CI 0.49; 0.66) while elastosonography had an AUC of 0.58 (95% CI 0.49; 0.67) when used individually. SMI together with elastosonography had AUC of 0.62 (95% CI 0.52; 0.71). TI-RADS had AUC of 0.67 (95% CI 0.59; 0.75). SMI and elastosonography applied together with TI-RADS had AUC of 0.69 (95% CI 0.61; 0.77).

Conclusion: In the real-world cohort of patients, the SMI technique and elastosonography slightly increase the AUC of TI-RADS. Taken individually, SMI and elastosonography do not have a very strong AUC.

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甲状腺结节的超微血管成像（SMI）和弹性成像：实时队列中的诊断价值。

目的：在临床实践中，甲状腺结节根据TI-RADS通过B型和彩色多普勒检查进行分类。本研究旨在评估超级微血管成像（SMI）和弹性成像在甲状腺结节恶性风险分层中可能增加的价值：方法：所有甲状腺结节患者均可进行针吸术。由经验丰富的操作人员进行标准检查并计算 TI-RADS，然后对结节进行 SMI 和弹性扫描。针吸结果作为金标准。统计分析计算了单独和连续应用这些技术的 ROC 曲线：在这项前瞻性研究中，我们分析了 251 名患者（平均年龄 58.6 岁 ± 14 岁）的 260 个结节。11.2%为TI-RADS 1，18.9%为TI-RADS 2，41.1%为TI-RADS 3，28.1%为TI-RADS 4，0.8%为TI-RADS 5。SMI 技术的 AUC 为 0.57（95% CI 0.49；0.66），而单独使用弹性超声造影的 AUC 为 0.58（95% CI 0.49；0.67）。SMI 与弹性造影结合使用的 AUC 为 0.62 (95% CI 0.52; 0.71)。TI-RADS 的 AUC 为 0.67 (95% CI 0.59; 0.75)。SMI和弹性造影与TI-RADS一起应用的AUC为0.69 (95% CI 0.61; 0.77)：结论：在真实世界的患者队列中，SMI 技术和弹性成像技术可略微提高 TI-RADS 的 AUC。单独来看，SMI 和弹性成像的 AUC 并不高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.10

自引率

15.00%

发文量

133

期刊介绍： The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.