Outbreak of Ralstonia pickettii associated with contamination of saline products distributed internationally, the United Kingdom, 2024.

IF 9.9 2区医学 Q1 INFECTIOUS DISEASES

Eurosurveillance Pub Date : 2024-07-01 DOI:10.2807/1560-7917.ES.2024.29.27.2400384

Mike Saunders, Amy Weaver, Rebecca Stretch, D Jeyaratnam, Mariyam Mirfenderesky, David Elliott, Charlotte Patterson, David Williams, Dervla Td Kenna, Jack Turton, Karen L Osman, Jane F Turton, Colin S Brown, Jwt Elston

引用次数: 0

Abstract

We describe an outbreak of Ralstonia pickettii in the United Kingdom, with isolates genetically indistinguishable from a 2023 Australian outbreak linked to internationally distributed saline solutions. Confirmed cases (n = 3) had bacteraemia, clinically relevant infection, indwelling venous lines and frequent healthcare contact. Multi-stakeholder intervention was required including product recall and risk communications. We recommend a low threshold for investigating clusters of Ralstonia species and similar opportunistic pathogens, considering contaminated product sources. Effective mitigation requires multi-agency partnership and international collaboration.

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与国际销售的生理盐水产品污染有关的 Ralstonia pickettii 疫情，英国，2024 年。

我们描述了英国爆发的 Ralstonia pickettii疫情，其分离物在遗传学上与 2023 年澳大利亚爆发的疫情无异，均与国际销售的生理盐水有关。确诊病例（n = 3）有菌血症、临床相关感染、留置静脉管和频繁的医护接触。需要多方利益相关者进行干预，包括产品召回和风险沟通。考虑到受污染产品的来源，我们建议采用较低的阈值来调查 Ralstonia 菌群和类似的机会性病原体。有效的缓解措施需要多机构合作和国际协作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eurosurveillance INFECTIOUS DISEASES-

CiteScore

32.70

自引率

2.10%

发文量

430

审稿时长

3-8 weeks

期刊介绍： Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.