Big data in sarcoidosis.

IF 2.8 3区医学 Q2 RESPIRATORY SYSTEM

Current Opinion in Pulmonary Medicine Pub Date : 2024-09-01 Epub Date: 2024-07-05 DOI:10.1097/MCP.0000000000001102

Natalia V Rivera

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引用次数: 0

Abstract

Purpose of review: This review provides an overview of recent advancements in sarcoidosis research, focusing on collaborative networks, phenotype characterization, and molecular studies. It highlights the importance of collaborative efforts, phenotype characterization, and the integration of multilevel molecular data for advancing sarcoidosis research and paving the way toward personalized medicine.

Recent findings: Sarcoidosis exhibits heterogeneous clinical manifestations influenced by various factors. Efforts to define sarcoidosis endophenotypes show promise, while technological advancements enable extensive molecular data generation. Collaborative networks and biobanks facilitate large-scale studies, enhancing biomarker discovery and therapeutic protocols.

Summary: Sarcoidosis presents a complex challenge due to its unknown cause and heterogeneous clinical manifestations. Collaborative networks, comprehensive phenotype delineation, and the utilization of cutting-edge technologies are essential for advancing our understanding of sarcoidosis biology and developing personalized medicine approaches. Leveraging large-scale epidemiological resources and biobanks and integrating multilevel molecular data offer promising avenues for unraveling the disease's heterogeneity and improving patient outcomes.

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肉样瘤病的大数据。

综述的目的：本综述概述了肉样瘤病研究的最新进展，重点关注协作网络、表型特征描述和分子研究。它强调了协作努力、表型特征描述和多层次分子数据整合对于推进肉样瘤病研究和为个性化医疗铺平道路的重要性：肉样瘤病的临床表现受多种因素的影响，具有异质性。界定肉样瘤病内分型的努力显示了前景，而技术进步使广泛的分子数据生成成为可能。协作网络和生物库为大规模研究提供了便利，从而促进了生物标志物的发现和治疗方案的制定。协作网络、全面的表型描述和尖端技术的利用对于增进我们对肉样瘤病生物学的了解和开发个性化医疗方法至关重要。利用大规模流行病学资源和生物库以及整合多层次分子数据，为揭示该疾病的异质性和改善患者预后提供了前景广阔的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Pulmonary Medicine 医学-呼吸系统

CiteScore

6.20

自引率

0.00%

发文量

109

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Pulmonary Medicine is a highly regarded journal offering insightful editorials and on-the-mark invited reviews, covering key subjects such as asthma; cystic fibrosis; infectious diseases; diseases of the pleura; and sleep and respiratory neurobiology. Published bimonthly, each issue of Current Opinion in Pulmonary Medicine introduces world renowned guest editors and internationally recognized academics within the pulmonary field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.