Long-term Outcomes of Poly-4-Hydroxybutyrate (P4HB) in Aesthetic Breast Surgery.

IF 3 2区医学 Q1 SURGERY

Aesthetic Surgery Journal Pub Date : 2024-11-15 DOI:10.1093/asj/sjae145

Nicholas R Sinclair, William P Adams

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引用次数: 0

Abstract

Background: Over the past decade, the use of poly-4-hydroxybutyrate (P4HB) in aesthetic breast surgery has grown in popularity. Published data on long-term outcomes, however, is scarce.

Objectives: The purpose of this study was to assess long-term outcomes with utilization of P4HB in various aesthetic breast procedures.

Methods: A retrospective review of all patients undergoing breast procedures with P4HB was performed by the senior author between July 2012 and March 2022. All patients with greater than 1 year of follow-up were evaluated, including demographics, surgical indications, complications, secondary procedures, and patient satisfaction. A Kruskal-Wallis test was performed to assess the stability of satisfaction over time.

Results: A total of 248 patients were evaluated. The mean follow-up length was 2.9 years (range, 1-9.3 years). The most common surgical indication was breast ptosis, which comprised 68% (n = 167) of patients. The overall complication rate was 8.0% (n = 20), with an unplanned reoperation rate of 2.8% (n = 7). Across the entire study population, the mean satisfaction score was 3.42 out of 4. When satisfaction scores were compared to follow-up length, Kruskal-Wallis test demonstrated no statistical differences (H = 18.2, P = .89, degrees of freedom [df]= 2), suggesting stability of satisfaction over time.

Conclusions: This study presents the senior author's entire experience with P4HB across a wide range of aesthetic breast procedures. With an average follow-up length of almost 3 years, P4HB appears to be a both safe and effective tool to support soft tissue in aesthetic breast surgery. Further, high patient satisfaction appears stable.

Level of evidence: 4:

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聚 4-羟丁酸（P4HB）在乳房美容手术中的长期效果。

背景：在过去十年中，聚 4-羟基丁酸（P4HB）在乳房美容手术中的应用日益普及。然而，有关长期疗效的公开数据却很少：本研究旨在评估在各种乳房美容手术中使用 P4HB 的长期疗效：方法：对资深作者（WPA）在 2012 年 7 月至 2022 年 3 月期间使用 P4HB 进行乳房手术的所有患者进行回顾性研究。对所有随访一年以上的患者进行了评估，包括人口统计学、手术适应症、并发症、二次手术和患者满意度。采用Kruskal-Wallis检验评估满意度随时间变化的稳定性：结果：共对 248 名患者进行了评估。平均随访时间为 2.9 年（1-9.3 年）。最常见的手术适应症是乳房下垂，占患者总数的 68%（167 人）。总体并发症发生率为 8.0%（20 人），非计划再手术率为 2.8%（7 人）。当将满意度得分与随访时间进行比较时，Kruskal-Wallis 检验显示无统计学差异（H = 18.2，P = 0.89，df = 2），这表明满意度随时间的推移保持稳定：本研究介绍了资深作者使用 P4HB 进行各种乳房美容手术的全部经验。平均随访时间将近 3 年，P4HB 似乎是乳房美容手术中支撑软组织的一种既安全又有效的工具。此外，患者的高满意度似乎也很稳定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aesthetic Surgery Journal SURGERY-

CiteScore

6.20

自引率

20.70%

发文量

309

审稿时长

6-12 weeks

期刊介绍： Aesthetic Surgery Journal is a peer-reviewed international journal focusing on scientific developments and clinical techniques in aesthetic surgery. The official publication of The Aesthetic Society, ASJ is also the official English-language journal of many major international societies of plastic, aesthetic and reconstructive surgery representing South America, Central America, Europe, Asia, and the Middle East. It is also the official journal of the British Association of Aesthetic Plastic Surgeons, the Canadian Society for Aesthetic Plastic Surgery and The Rhinoplasty Society.