{"title":"Different fractionation schedules in radiation treatment of cerebral metastases.","authors":"F D'Elia, I Bonucci, G P Biti, L Pirtoli","doi":"10.3109/02841868609136400","DOIUrl":null,"url":null,"abstract":"<p><p>Multiple daily fractionation (MDF) was compared, in a cooperative study, with conventional fractionation (CF) in the radiation treatment of brain metastases. The 103 patients treated by MDF and the 44 given CF showed a similar response, in terms of neurologic improvement, survival, quality of residual life, and treatment-related morbidity. The hypothesis that MDF might give a better therapeutic ratio than CF was not confirmed in the present series. The short time period required gives MDF advantages in clinical practice.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 3","pages":"181-4"},"PeriodicalIF":0.0000,"publicationDate":"1986-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136400","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica. Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841868609136400","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
Multiple daily fractionation (MDF) was compared, in a cooperative study, with conventional fractionation (CF) in the radiation treatment of brain metastases. The 103 patients treated by MDF and the 44 given CF showed a similar response, in terms of neurologic improvement, survival, quality of residual life, and treatment-related morbidity. The hypothesis that MDF might give a better therapeutic ratio than CF was not confirmed in the present series. The short time period required gives MDF advantages in clinical practice.
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