Recent advances in electrochemical biosensors for the determination of biomolecules on modified and unmodified electrodes

IF 2.2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
S. Thulasiprevinnah, Shahid Bashir, K. Ramesh, S. Ramesh
{"title":"Recent advances in electrochemical biosensors for the determination of biomolecules on modified and unmodified electrodes","authors":"S. Thulasiprevinnah,&nbsp;Shahid Bashir,&nbsp;K. Ramesh,&nbsp;S. Ramesh","doi":"10.1007/s13738-024-03050-6","DOIUrl":null,"url":null,"abstract":"<div><p>Electrochemical sensors are a class of sensors in which the electrode is the transducer element. In this type of sensor, an electrode is a critical component employed as a solid support for immobilizing biomolecules and electron movement. The material, fabrication approach, and design affect the electrode’s structure and properties, which ultimately determine the biosensor’s performance, including sensitivity, selectivity, limit of detection, and dynamic range. They also influence the biosensor’s cost, manufacturability, disposability, and measurement capabilities. This review article describes recent advances in using non-modified and modified electrodes as support in electrochemical biosensors for the determination of biomolecules. It summarizes recent work on modifying electrodes using carbonaceous materials, conducting polymers, MXenes, and transition metal oxide nanomaterials. It also focuses on current techniques, types of materials, designs, simulation studies, and fabrication methods on unmodified and modified electrodes. Lastly, challenges in electrochemical sensors were identified, and future directions were presented comprehensively.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":676,"journal":{"name":"Journal of the Iranian Chemical Society","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Iranian Chemical Society","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s13738-024-03050-6","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Electrochemical sensors are a class of sensors in which the electrode is the transducer element. In this type of sensor, an electrode is a critical component employed as a solid support for immobilizing biomolecules and electron movement. The material, fabrication approach, and design affect the electrode’s structure and properties, which ultimately determine the biosensor’s performance, including sensitivity, selectivity, limit of detection, and dynamic range. They also influence the biosensor’s cost, manufacturability, disposability, and measurement capabilities. This review article describes recent advances in using non-modified and modified electrodes as support in electrochemical biosensors for the determination of biomolecules. It summarizes recent work on modifying electrodes using carbonaceous materials, conducting polymers, MXenes, and transition metal oxide nanomaterials. It also focuses on current techniques, types of materials, designs, simulation studies, and fabrication methods on unmodified and modified electrodes. Lastly, challenges in electrochemical sensors were identified, and future directions were presented comprehensively.

Graphical Abstract

Abstract Image

在改性和未改性电极上测定生物分子的电化学生物传感器的最新进展
电化学传感器是一类以电极为换能器元件的传感器。在这类传感器中,电极是作为固定生物分子和电子运动的固体支撑的关键部件。电极的材料、制造方法和设计会影响电极的结构和特性,最终决定生物传感器的性能,包括灵敏度、选择性、检测极限和动态范围。它们还会影响生物传感器的成本、可制造性、可抛弃性和测量能力。这篇综述文章介绍了在电化学生物传感器中使用非改性和改性电极作为支持物测定生物分子的最新进展。文章总结了使用碳质材料、导电聚合物、MXenes 和过渡金属氧化物纳米材料改性电极的最新研究成果。报告还重点介绍了当前的技术、材料类型、设计、模拟研究以及未改性和改性电极的制造方法。最后,还指出了电化学传感器所面临的挑战,并全面介绍了未来的发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.40
自引率
8.30%
发文量
230
审稿时长
5.6 months
期刊介绍: JICS is an international journal covering general fields of chemistry. JICS welcomes high quality original papers in English dealing with experimental, theoretical and applied research related to all branches of chemistry. These include the fields of analytical, inorganic, organic and physical chemistry as well as the chemical biology area. Review articles discussing specific areas of chemistry of current chemical or biological importance are also published. JICS ensures visibility of your research results to a worldwide audience in science. You are kindly invited to submit your manuscript to the Editor-in-Chief or Regional Editor. All contributions in the form of original papers or short communications will be peer reviewed and published free of charge after acceptance.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信