Robotic pyelolithotomy for the treatment of large renal stones: a single-center experience over seven years.

Stefano Moretto, Michele Zazzara, Filippo Marino, Arjan Nazaraj, Marcello Scarcia, Giuseppe M Ludovico
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Abstract

Background: Urolithiasis prevalence varies globally between 1-20%, influenced by regional factors. Robotic pyelolithotomy (RPL) presents an interesting alternative to PCNL, considered the gold standard for symptomatic stones smaller than 20 mm, as it carries a risk of significant complications. However, studies on RPL are limited, especially in anatomically complex cases, where RPL proves to be particularly useful. The study aims to update and review outcomes of RPL in a high-volume robotic center.

Methods: A retrospective analysis of 153 patients treated with RPL for staghorn kidney stones at a single center from February 2016 to December 2023 was conducted. Data including demographics, preoperative renal function, stone characteristics, operative and postoperative outcomes, and costs were collected. Stone-free rates (SFR) and complications were assessed at follow-up intervals up to 12 months post-surgery.

Results: The study showed an initial 3-month stone-free rate (SFR) of 93.5%, which decreased to 83.5% at 12-months. This trend may reflect new stone formation rather than procedure failure. Sub-analysis revealed a significant difference in SFR between patients with pelvic and pyelocalyceal stones at each follow-up. Multivariate regression analysis identified in the pyelocalyceal group that higher BMI and larger stones were associated with higher failure rates at both 6 and 12 months.

Conclusions: RPL is a safe and effective treatment for large renal stones, offering a high SFR and low complication rate. It is particularly beneficial in cases with complex anatomy or requiring concurrent renal procedures. However, patient selection is crucial, considering factors like stone location and size. Further research is needed to compare RPL with other treatment methods.

机器人肾盂切开术治疗巨大肾结石:单中心七年来的经验。
背景:受地区因素影响,全球尿路结石发病率在 1-20% 之间。机器人肾盂取石术(RPL)被认为是治疗小于20毫米的无症状结石的金标准,是PCNL的一种有趣的替代方法,因为它有可能引起严重的并发症。然而,关于RPL的研究却很有限,尤其是在解剖结构复杂的病例中,RPL被证明特别有用。本研究旨在更新和回顾一个高容量机器人中心的 RPL 结果:方法:对2016年2月至2023年12月在一个中心接受RPL治疗的153例鹿角状肾结石患者进行了回顾性分析。收集的数据包括人口统计学、术前肾功能、结石特征、手术和术后结果以及费用。术后随访至12个月,评估无结石率(SFR)和并发症:研究显示,最初 3 个月的无结石率(SFR)为 93.5%,12 个月时降至 83.5%。这一趋势可能反映了新结石的形成,而非手术失败。子分析显示,盆腔结石和肾盂萼膜结石患者在每次随访时的无结石率都有显著差异。多变量回归分析显示,在肾盂结石组中,较高的体重指数和较大的结石与6个月和12个月的较高失败率有关:RPL是一种安全有效的治疗大块肾结石的方法,具有较高的SFR和较低的并发症发生率。它对解剖结构复杂或需要同时进行肾脏手术的病例尤其有益。不过,考虑到结石位置和大小等因素,患者的选择至关重要。还需要进一步研究,将RPL与其他治疗方法进行比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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