Programmatic implications of a sub-national TB prevalence survey in India.

IF 3.4 3区医学 Q2 INFECTIOUS DISEASES

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-07-01 DOI:10.5588/ijtld.23.0456

G Prathiksha, S Selvaraju, K Thiruvengadam, A Frederick, H Murugesan, P Rajendran, K Nagarajan, M Kumar, R Krishnan, P Kumaran, T S Selvavinayagam, C Padmapriyadarsini

{"title":"Programmatic implications of a sub-national TB prevalence survey in India.","authors":"G Prathiksha, S Selvaraju, K Thiruvengadam, A Frederick, H Murugesan, P Rajendran, K Nagarajan, M Kumar, R Krishnan, P Kumaran, T S Selvavinayagam, C Padmapriyadarsini","doi":"10.5588/ijtld.23.0456","DOIUrl":null,"url":null,"abstract":"<p><p><sec><title>BACKGROUND</title>Subnational TB estimates are crucial for making informed decisions to tailor TB control activities to local TB epidemiology.</sec><sec><title>METHODS</title>A cross-sectional survey was conducted among 143,005 individuals in Tamil Nadu, India. Participants were screened for symptoms and underwent chest X-ray (CXR). Participants with symptoms of TB and/or abnormal CXR were tested for TB using Xpert, smear, and liquid culture.</sec><sec><title>RESULTS</title>The prevalence of microbiologically confirmed pulmonary TB (MCPTB) was 212 (95% CI 184-239) per 100,000 population. The prevalence-to-notification ratio (P:N) in the state was 2.05 (95% CI 1.8-2.29). Low body mass index and diabetes together had a population attributable fraction of 54.15 (95% CI 45.68-61.97). Approximately 39% of the TB cases were asymptomatic and were identified only by CXR screening. In the general population, only 26.9% sought care at a health facility among those with symptoms suggestive of TB.</sec><sec><title>CONCLUSION</title>The programme needs to prioritise screening with CXR to potentially detect cases earlier and curtail the transmission and upscale molecular tests in the selected population to increase the yield of case finding. Innovative health education strategies must be devised to address health-seeking behaviour.</sec>.</p>","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":null,"pages":null},"PeriodicalIF":3.4000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Tuberculosis and Lung Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5588/ijtld.23.0456","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

BACKGROUNDSubnational TB estimates are crucial for making informed decisions to tailor TB control activities to local TB epidemiology.METHODSA cross-sectional survey was conducted among 143,005 individuals in Tamil Nadu, India. Participants were screened for symptoms and underwent chest X-ray (CXR). Participants with symptoms of TB and/or abnormal CXR were tested for TB using Xpert, smear, and liquid culture.RESULTSThe prevalence of microbiologically confirmed pulmonary TB (MCPTB) was 212 (95% CI 184-239) per 100,000 population. The prevalence-to-notification ratio (P:N) in the state was 2.05 (95% CI 1.8-2.29). Low body mass index and diabetes together had a population attributable fraction of 54.15 (95% CI 45.68-61.97). Approximately 39% of the TB cases were asymptomatic and were identified only by CXR screening. In the general population, only 26.9% sought care at a health facility among those with symptoms suggestive of TB.CONCLUSIONThe programme needs to prioritise screening with CXR to potentially detect cases earlier and curtail the transmission and upscale molecular tests in the selected population to increase the yield of case finding. Innovative health education strategies must be devised to address health-seeking behaviour..

查看原文本刊更多论文

印度次国家级结核病流行率调查对计划的影响。

背景国家以下各级的结核病估计数对于根据当地结核病流行情况制定明智的结核病控制活动至关重要。参与者接受了症状筛查和胸部 X 光检查（CXR）。结果经微生物确诊的肺结核（MCPTB）发病率为每 10 万人 212 例（95% CI 184-239）。该州的发病率与通知率（P:N）为 2.05（95% CI 1.8-2.29）。低体重指数和糖尿病的人口可归因比例为 54.15（95% CI 45.68-61.97）。约 39% 的肺结核病例无症状，仅通过 CXR 筛查发现。在普通人群中，只有 26.9% 的人在出现肺结核症状时到医疗机构就诊。必须制定创新的健康教育战略，以解决寻求健康的行为问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Tuberculosis and Lung Disease 医学-传染病学

CiteScore

4.90

自引率

20.00%

发文量

266

审稿时长

2 months

期刊介绍： The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.