China's Modified Version of Sniffin' Sticks 12-Identification Test Used in Chinese Parkinson's Disease and Multiple System Patients: Comparison of Three Olfactory Testing Methods.

IF 2.1 4区医学 Q3 CLINICAL NEUROLOGY

Parkinson's Disease Pub Date : 2024-06-25 eCollection Date: 2024-01-01 DOI:10.1155/2024/3561881

Huijing Liu, Wei Du, Shuhua Li, Ying Jin, Haibo Chen, Wen Su

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引用次数: 0

Abstract

Objectives: The aim of this study was to compare the Sniffin' Sticks 12-identification test (SIT-12), China-modified version of the SIT-12 test (Ch-SIT-12) and brief smell identification test for Chinese (B-SITC) in Chinese population of Parkinson's disease (PD) and multiple system atrophy (MSA).

Methods: 36 patients with PD and 7 patients with MSA were enrolled in this study. Three olfactory testing methods (SIT-12, Ch-SIT-12, and B-SITC) were used to test the olfactory function in all participants. Furthermore, demographic and clinical data were collected.

Results: There was no significant difference between three olfactory tests in patients with PD (B-SITC vs. SIT-12: P=0.508; Ch-SIT-12 vs. B-SITC: P=0.146; and SIT-12 vs. Ch-SIT-12: P=0.375). Tremor-dominant (TD) subtypes have better olfactory function than akinetic-rigid dominant (ARD) subtypes when using Ch-SIT-12 (77.8% vs. 29.6%, P=0.019) or B-SITC (55.6% vs. 14.8%, P=0.026). There was a statistical difference between the PD and MSA using Ch-SIT-12 to test the olfactory function (P=0.046).

Conclusions: Our results indicated that SIT-12, Ch-SIT-12 and B-SITC can be used for the detection of olfactory dysfunction in Chinese population of PD. TD subtypes may have better olfactory function than ARD subtypes. In addition, Ch-SIT-12 may be used to differentiate PD from MSA, but that should be confirmed in a larger population.

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中国帕金森病和多系统患者使用的改良版 "闻香棒 "12-识别测试：三种嗅觉测试方法的比较。

研究目的本研究旨在比较中国帕金森病（PD）和多系统萎缩（MSA）患者的嗅棒12识别测试（SIT-12）、中国改良版SIT-12测试（Ch-SIT-12）和中文简短气味识别测试（B-SITC）。采用三种嗅觉测试方法（SIT-12、Ch-SIT-12 和 B-SITC）测试所有参与者的嗅觉功能。此外，还收集了人口统计学和临床数据：结果：PD 患者的三种嗅觉测试之间没有明显差异（B-SITC vs. SIT-12：P=0.508；Ch-SIT-12 vs. B-SITC：P=0.146；SIT-12 vs. Ch-SIT-12：P=0.375）。使用 Ch-SIT-12（77.8% 对 29.6%，P=0.019）或 B-SITC（55.6% 对 14.8%，P=0.026）时，震颤显性（TD）亚型的嗅觉功能优于动觉僵直显性（ARD）亚型。使用 Ch-SIT-12 测试嗅觉功能的 PD 和 MSA 之间存在统计学差异（P=0.046）：我们的研究结果表明，SIT-12、Ch-SIT-12 和 B-SITC 可用于检测中国 PD 患者的嗅觉功能障碍。TD亚型的嗅觉功能可能优于ARD亚型。此外，Ch-SIT-12 也可用于区分 PD 和 MSA，但这需要在更多的人群中得到证实。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Parkinson's Disease CLINICAL NEUROLOGY-

CiteScore

5.80

自引率

3.10%

发文量

审稿时长

18 weeks

期刊介绍： Parkinson’s Disease is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the epidemiology, etiology, pathogenesis, genetics, cellular, molecular and neurophysiology, as well as the diagnosis and treatment of Parkinson’s disease.