Impact of Chronic Consumption of Herbal Rooibos on Cardiovascular Function in Adults with Cardiovascular Risk.

IF 1.7 3区 农林科学 Q4 CHEMISTRY, MEDICINAL
Journal of medicinal food Pub Date : 2024-10-01 Epub Date: 2024-07-03 DOI:10.1089/jmf.2024.0012
Maria Diana Hartnick, Jeanine L Marnewick, Penelope Engel-Hills, Merlisa Kemp, Kobus Pretorius, Stanley Lekata, Corrie Uys
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引用次数: 0

Abstract

The prevalence of cardiovascular disease (CVD) has increased in South Africa, emphasizing the importance of prevention strategies. This study used echocardiography to investigate the impact of Rooibos on cardiovascular function in those at risk of CVD. This research aims to contribute to understanding its effects on reducing cardiovascular risk factors. The study design involved a 12-week randomized, parallel, double-blinded, placebo-controlled dietary intervention trial using capsules containing standardized water-soluble extracts of green and traditional fermented Rooibos alongside a placebo control. Echocardiography was incorporated as a diagnostic imaging tool to assess cardiac function in the participant cohort. Aorta (AO) dimensions showed no significant change in any intervention group. Left atrium (LA) reduced in size from 3.832 ± 0.071 cm to 3.675 ± 0.067 cm (P = 0.01). There was no significant change in LA/AO ratio in any intervention group. Interventricular septum diameter in the placebo group decreased from 1.334 ± 0.030 cm to 1.250 ± 0.025 cm (P = 0.002), with no significance in fermented Rooibos, while green Rooibos resulted in a decrease from 1.282 ± 0.036 cm to 1.186 ± 0.029 cm (P = 0.002). Left ventricle posterior wall (LVPW) showed no significant changes in any of the intervention group. The left ventricle mass in the placebo and green Rooibos groups demonstrated no significance changes, while fermented Rooibos caused a decrease from 204.102 ± 7.102 g to 191.394 ± 6.707 g (P = 0.015). The phytochemical bioactive components, such as the polyphenolic antioxidants present in green and fermented Rooibos, improved cardiovascular function. This study confirms the effectiveness of echocardiography as imaging tool for assessing cardiac function in this particular population. Regular Rooibos consumption may offer promising therapeutic benefits for preventing and managing CVD risk.

长期饮用草本路依保斯对有心血管风险的成年人心血管功能的影响
南非的心血管疾病(CVD)发病率有所上升,这凸显了预防策略的重要性。本研究使用超声心动图来调查路依保斯对心血管疾病高危人群心血管功能的影响。这项研究旨在帮助人们了解路依保斯对减少心血管风险因素的作用。研究设计包括一项为期 12 周的随机、平行、双盲、安慰剂对照膳食干预试验,使用含有绿色和传统发酵路依保斯标准化水溶性提取物的胶囊和安慰剂对照。超声心动图是一种诊断成像工具,用于评估参与者的心脏功能。任何干预组的主动脉(AO)尺寸均无明显变化。左心房(LA)尺寸从 3.832 ± 0.071 厘米降至 3.675 ± 0.067 厘米(P = 0.01)。任何干预组的 LA/AO 比值均无明显变化。安慰剂组的室间隔直径从 1.334 ± 0.030 厘米降至 1.250 ± 0.025 厘米(P = 0.002),发酵路依保斯无明显变化,而绿色路依保斯则从 1.282 ± 0.036 厘米降至 1.186 ± 0.029 厘米(P = 0.002)。干预组的左心室后壁(LVPW)均无明显变化。安慰剂组和绿色路依保斯组的左心室质量无明显变化,而发酵路依保斯组的左心室质量则从 204.102 ± 7.102 克降至 191.394 ± 6.707 克(P = 0.015)。绿色和发酵路依保斯中的植物化学生物活性成分,如多酚抗氧化剂,可改善心血管功能。这项研究证实了超声心动图作为成像工具评估这一特殊人群心功能的有效性。经常饮用路依保斯可为预防和控制心血管疾病风险带来良好的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of medicinal food
Journal of medicinal food 医学-食品科技
CiteScore
4.50
自引率
0.00%
发文量
154
审稿时长
4.5 months
期刊介绍: Journal of Medicinal Food is the only peer-reviewed journal focusing exclusively on the medicinal value and biomedical effects of food materials. International in scope, the Journal advances the knowledge of the development of new food products and dietary supplements targeted at promoting health and the prevention and treatment of disease.
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