Human Immunodeficiency Virus Preexposure Prophylaxis Awareness and Acceptability among Men Who Have Sex with Men and Transgender Persons in India: Systematic Review and Meta-analysis.

IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Indian journal of public health Pub Date : 2024-04-01 Epub Date: 2024-06-29 DOI:10.4103/ijph.ijph_1027_23
Adhish Kumar Sethi, Partha Haldar, Shashi Kant, Sanjay Kumar Rai, Shobini Rajan, Parveen Kumar
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引用次数: 0

Abstract

With increasing importance being given to preexposure prophylaxis (PrEP) for human immunodeficiency virus prevention among men who have sex with men (MSM) and transgender persons (TG), we undertook a systematic review and meta-analysis of PrEP awareness and acceptability among these key populations in India, and their sociodemographic and behavioral determinants. The systematic review was registered with PROSPERO (CRD42023390508). Studies were included if they provided quantitative data on PrEP awareness or acceptability among MSM or TG in India. MEDLINE, Scopus, Web of Science, and Embase were searched from inception to February 29, 2024, using keywords and database-specific terms. Relevant websites were also searched. Critical appraisal was done using the Joanna Briggs Institute Checklist for Prevalence Studies. Random-effects meta-analysis was done for common outcomes reported by the studies. Reporting was as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses 2020 statement. Ten studies providing cross-sectional data, mostly from South West India, were included for qualitative synthesis. All were conducted in settings where PrEP was not available. The pooled prevalence among MSM and TG was 18.7% (95% confidence interval [CI] 8.7%, 28.7%) for awareness and 79.8% (95% CI 57.4%, 100.0%) for willingness to use daily oral PrEP. This review highlights the felt need for PrEP among MSM and TG in India. Further research is needed to understand user attitudes in different parts of the country.

印度男男性行为者和变性者对人类免疫缺陷病毒三暴露预防措施的认识和接受程度:系统回顾和元分析》。
随着人们越来越重视在男男性行为者(MSM)和变性人(TG)中采用暴露前预防疗法(PrEP)来预防人类免疫缺陷病毒,我们对印度这些关键人群对 PrEP 的认知度和接受度及其社会人口和行为决定因素进行了系统综述和荟萃分析。该系统综述已在 PROSPERO 注册(CRD42023390508)。如果研究提供了有关印度 MSM 或 TG 对 PrEP 的认知度或接受度的定量数据,则纳入该研究。使用关键词和数据库特定术语检索了 MEDLINE、Scopus、Web of Science 和 Embase,检索期从开始到 2024 年 2 月 29 日。还搜索了相关网站。采用乔安娜-布里格斯研究所(Joanna Briggs Institute)流行病学研究核对表进行了严格评估。对研究报告的共同结果进行了随机效应荟萃分析。按照《2020 年系统综述和荟萃分析首选报告项目声明》进行报告。定性综合纳入了十项提供横断面数据的研究,其中大部分来自印度西南部。所有研究均在未提供 PrEP 的环境中进行。在 MSM 和 TG 中,对 PrEP 的了解程度为 18.7%(95% 置信区间 [CI]:8.7%, 28.7%),愿意使用每日口服 PrEP 的比例为 79.8%(95% 置信区间 [CI]:57.4%, 100.0%)。本综述强调了印度男男性行为者和女性同性恋者对 PrEP 的需求。需要进一步开展研究,以了解印度不同地区用户的态度。
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来源期刊
Indian journal of public health
Indian journal of public health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.40
自引率
0.00%
发文量
92
审稿时长
21 weeks
期刊介绍: Indian Journal of Public Health is a peer-reviewed international journal published Quarterly by the Indian Public Health Association. It is indexed / abstracted by the major international indexing systems like Index Medicus/MEDLINE, SCOPUS, PUBMED, etc. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles. The Indian Journal of Public Health publishes articles of authors from India and abroad with special emphasis on original research findings that are relevant for developing country perspectives including India. The journal considers publication of articles as original article, review article, special article, brief research article, CME / Education forum, commentary, letters to editor, case series reports, etc. The journal covers population based studies, impact assessment, monitoring and evaluation, systematic review, meta-analysis, clinic-social studies etc., related to any domain and discipline of public health, specially relevant to national priorities, including ethical and social issues. Articles aligned with national health issues and policy implications are prefered.
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