Relationship between COVID-19 and orofacial clefts.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-01 DOI:10.4149/gpb_2024012

Agáta Molnárová, Dagmar Fekiačová, Jozef Záhumenský, Monika Rosoľanková, Eduard Ujházy, Michal Dubovický, Drahomír Palenčár

引用次数: 0

Abstract

The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test. The study showed significantly higher incidence of COVID-19 disease in the group of mothers who gave birth to a child with NSOFC in comparison to the group of mothers who gave birth to a child without NSOFC. Our results indicate the possible participation of the infection of COVID-19 in the formation of NSOFCs.

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COVID-19 与口面裂隙之间的关系。

该研究介绍了孕期感染 COVID-19 与非综合征性口面裂（NSOFC）之间的关系。研究的目的是比较一组 NSOFC 患儿和一组非 NSOFC 对照组患儿在母亲怀孕期间 COVID-19 的发病率。COVID-19通过聚合酶链式反应（PCR）检测进行确诊。研究结果表明，与生育非 NSOFC 患儿的母亲组相比，生育 NSOFC 患儿的母亲组的 COVID-19 发病率明显更高。我们的研究结果表明，COVID-19 感染可能参与了 NSOFC 的形成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.