Airborne pollen exposure and risk of hospital admission for allergic rhinitis in Beijing: A time-stratified case-crossover study

IF 4.6 2区医学 Q2 ALLERGY

Clinical and Translational Allergy Pub Date : 2024-07-02 DOI:10.1002/clt2.12380

Yuhui Ouyang, Jun Yang, Jingxuan Zhang, Yun Yan, Shengzhi Sun, Jiajia Wang, Xiaobo Li, Rui Chen, Luo Zhang

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引用次数: 0

Abstract

Background

Airborne pollen is a crucial risk factor in allergic rhinitis (AR). The severity of AR symptoms can vary based on pollen type and concentration. This study aimed to estimate the association between exposure to different pollen types and AR risk.

Methods

We obtained data from patients admitted to the Beijing Tongren Hospital for AR, and data on pollen concentration, meteorological factors, and fine particulate matter (PM_2.5) from 13 districts in Beijing from 2016 to 2019. We used a time-stratified case-crossover study design and calculated odds ratios (ORs) related to the risk of AR associated with a 10 grain/1000 mm² increase in total pollen concentrations for specific pollen types. A stratified analysis was conducted to assess whether the associations were varied by age and sex.

Results

The OR of AR associated with a 10 grain/1000 mm² increase in the 7-day average pollen concentration was 1.014 (95% CI: 1.014, 1.015), 1.076 (95% CI: 1.070, 1.082), 1.024 (95% CI: 1.023, 1.025), 1.042 (95% CI: 1.039, 1.045), 1.142 (95% CI: 1.137, 1.147), 1.092 (95% CI: 1.088, 1.097), 1.046 (95% CI: 1.035, 1.058), and 1.026 (95% CI: 1.024, 1.028) for total pollen, Ulmus, Cupressaceae, Populus, Fraxinus, Pinus, Betula, and Artemisia, respectively. Both tree pollen (Ulmus, Cupressaceae, Populus, Fraxinus, Betula, and Pinus) and weed pollen (Artemisia, Chenopodium, and Humulus) were correlated with an increased risk of AR. These associations remained consistent across distinct subgroups defined by both age and sex.

Conclusion

Exposure to pollen from trees and weeds might be associated with an increased risk of AR. This research provides valuable scientific support for both clinical practitioners and patients with AR regarding the hazards of pollen exposure.

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北京空气中花粉暴露与过敏性鼻炎入院风险：一项时间分层病例交叉研究。

背景：空气中的花粉是过敏性鼻炎（AR）的一个重要危险因素。花粉种类和浓度不同，过敏性鼻炎症状的严重程度也不同。本研究旨在估算暴露于不同花粉类型与过敏性鼻炎风险之间的关系：我们从北京同仁医院获得了因AR入院的患者数据，以及2016年至2019年北京13个区的花粉浓度、气象因素和细颗粒物（PM2.5）数据。我们采用了时间分层病例交叉研究设计，并计算了与特定花粉类型的总花粉浓度每增加 10 粒/1000 平方毫米相关的 AR 风险的几率比 (OR)。研究还进行了分层分析，以评估这些关联是否因年龄和性别而异：与 7 天平均花粉浓度增加 10 粒/1000 平方毫米相关的 AR OR 值分别为 1.014（95% CI：1.014，1.015）、1.076（95% CI：1.070，1.082）、1.024（95% CI：1.023，1.025）、1.042（95% CI：1.039，1.045）、1.142（95% CI：1.137，1.147）、1.092（95% CI：1.088，1.097）、1.046（95% CI：1.035，1.058）和 1.026（95% CI：1.024，1.028）。树木花粉（榆树、松柏科、杨树、梣树、桦树和松树）和杂草花粉（蒿、藜和葎草）都与 AR 风险的增加相关。这些关联在按年龄和性别划分的不同亚组中保持一致：结论：接触树木和杂草的花粉可能与 AR 风险增加有关。这项研究为临床医师和 AR 患者提供了有关接触花粉危害的宝贵科学依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Translational Allergy Immunology and Microbiology-Immunology

CiteScore

7.50

自引率

4.50%

发文量

117

审稿时长

12 weeks

期刊介绍： Clinical and Translational Allergy, one of several journals in the portfolio of the European Academy of Allergy and Clinical Immunology, provides a platform for the dissemination of allergy research and reviews, as well as EAACI position papers, task force reports and guidelines, amongst an international scientific audience. Clinical and Translational Allergy accepts clinical and translational research in the following areas and other related topics: asthma, rhinitis, rhinosinusitis, drug hypersensitivity, allergic conjunctivitis, allergic skin diseases, atopic eczema, urticaria, angioedema, venom hypersensitivity, anaphylaxis, food allergy, immunotherapy, immune modulators and biologics, animal models of allergic disease, immune mechanisms, or any other topic related to allergic disease.