In situ borneol-modified polyester with antibacterial adhesion and long-term fungal-repellent properties

IF 4.5 3区工程技术 Q1 CHEMISTRY, APPLIED

Reactive & Functional Polymers Pub Date : 2024-06-22 DOI:10.1016/j.reactfunctpolym.2024.105993

Zixu Xie , Chen Chen , Xinyu Chen , Fanqiang Bu , Guofeng Li , Pengfei Zhang , Xing Wang

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Abstract

Polyester is widely used in biomedical, textile, and food packaging fields. Therefore, enhancing it with antimicrobial properties would be a significant advancement. In this paper, a series of borneol-triazine polyesters (BTPs) with different structures are synthesized through room temperature polycondensation. The structure and composition of BTPs are systematically characterized by ¹H NMR, FTIR and GPC. Antimicrobial results reveal that the ability of BTPs to resist bacterial or fungal adhesion is directly related to the polymer structure. When the polymer chain of BTPs adopts a rigid structure, they exhibit excellent anti-adhesive and inhibitory performances against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). Meanwhile, the as-synthesized BTPs poses a fungal-repelling effect on common fungal strains (Aspergillus niger) for up to 30 d. Further studies have shown that a stereochemical structure brought by borneol is key for imparting effective antimicrobial properties to BTPs. In addition, BTPs are non-leaching materials with low cellular cytotoxicity. Taking into consideration, BTP provides a potential strategy for preparing a new class of antimicrobial polyester materials.

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具有抗菌粘附性和长期斥真菌特性的原位苯酚改性聚酯

聚酯广泛应用于生物医学、纺织和食品包装领域。因此，增强其抗菌性能将是一项重大进步。本文通过室温缩聚反应合成了一系列具有不同结构的龙脑-三嗪聚酯（BTPs）。通过 1H NMR、FTIR 和 GPC 对 BTPs 的结构和组成进行了系统表征。抗菌结果表明，BTPs 抵抗细菌或真菌粘附的能力与聚合物结构直接相关。当 BTPs 的聚合物链采用刚性结构时，它们对革兰氏阴性菌（大肠杆菌）和革兰氏阳性菌（金黄色葡萄球菌）都具有优异的抗粘附和抑制性能。进一步的研究表明，龙脑醇带来的立体化学结构是赋予 BTPs 有效抗菌特性的关键。此外，BTP 还具有低细胞毒性，是一种非浸出材料。有鉴于此，BTP 为制备新型抗菌聚酯材料提供了一种潜在的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reactive & Functional Polymers 工程技术-高分子科学

CiteScore

8.90

自引率

5.90%

发文量

259

审稿时长

27 days

期刊介绍： Reactive & Functional Polymers provides a forum to disseminate original ideas, concepts and developments in the science and technology of polymers with functional groups, which impart specific chemical reactivity or physical, chemical, structural, biological, and pharmacological functionality. The scope covers organic polymers, acting for instance as reagents, catalysts, templates, ion-exchangers, selective sorbents, chelating or antimicrobial agents, drug carriers, sensors, membranes, and hydrogels. This also includes reactive cross-linkable prepolymers and high-performance thermosetting polymers, natural or degradable polymers, conducting polymers, and porous polymers. Original research articles must contain thorough molecular and material characterization data on synthesis of the above polymers in combination with their applications. Applications include but are not limited to catalysis, water or effluent treatment, separations and recovery, electronics and information storage, energy conversion, encapsulation, or adhesion.