Effect of metabolic syndrome and its components on the risk and prognosis of cervical cancer: A literature review

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2024-06-22 DOI:10.1016/j.gore.2024.101438

Rogers Kajabwangu , Jonathan Izudi , Joel Bazira , Frank Ssedyabane , Stuart Turanzomwe , Abraham Birungi , Joseph Ngonzi , Francis Bajunirwe , Thomas C Randall

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引用次数: 0

Abstract

Despite the global implementation of preventive strategies against Human Papilloma Virus (HPV) infection, the incidence of invasive cervical cancer rose by nearly 1.3-fold, from 471,000 annual cases in 2000 to 604,000 cases in 2020. With over 340,000 deaths annually, cervical cancer is the fourth leading cause of cancer mortality in women globally.

There is a need to understand other factors besides HPV such as metabolic syndrome (MetS) that potentially influence the onset and progression of cervical cancer. In this narrative review, we describe evidence showing that Metabolic syndrome (MetS) increases the risk for cervical cancer and worsens its prognosis. Combined screening for MetS and cervical cancer has potential to significantly reduce morbidity and mortality in women with cervical cancer.

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代谢综合征及其组成部分对宫颈癌风险和预后的影响：文献综述

尽管全球都在实施针对人类乳头瘤病毒（HPV）感染的预防策略，但浸润性宫颈癌的发病率仍上升了近 1.3 倍，从 2000 年的 47.1 万例增加到 2020 年的 60.4 万例。宫颈癌每年导致超过 34 万人死亡，是全球女性癌症死亡的第四大原因。除了 HPV 之外，我们还需要了解可能影响宫颈癌发病和进展的其他因素，如代谢综合征（MetS）。在这篇叙述性综述中，我们描述了有证据显示代谢综合征（MetS）会增加患宫颈癌的风险并恶化其预后。联合筛查代谢综合征和宫颈癌有可能显著降低宫颈癌妇女的发病率和死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.