Routine Versus Selective Distal Perfusion Catheter Use in Venoarterial Extracorporeal Membrane Oxygenation.

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL
ASAIO Journal Pub Date : 2025-01-01 Epub Date: 2024-06-28 DOI:10.1097/MAT.0000000000002264
Kevin G Buda, Emilie C Robinson, Jessica Titus, Peter M Eckman, Ivan Chavez, Ellen Cravero, Larissa Stanberry, Katarzyna Hryniewicz
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Abstract

Although current studies support the use of prophylactic distal perfusion catheters (DPCs) to decrease limb ischemia in patients on venoarterial extracorporeal membrane oxygenation (VA ECMO), methods for monitoring limb ischemia differ between studies. We evaluated the safety of a selective rather than prophylactic DPC strategy at a single center with a well-established protocol for limb ischemia monitoring. Distal perfusion catheters were placed selectively if there was evidence of hypoperfusion at any point until decannulation. All patients were followed daily by vascular surgery with continuous regional saturation monitoring. Of 188 patients supported with VA ECMO, there were no significant differences in baseline characteristics between patients with upfront, delayed, and no DPC. Thirty day mortality was highest in patients with an upfront DPC (56% in the upfront DPC group, 19% in the delayed DPC group, and 22% in the no-DPC group, p < 0.001). The incidence of major bleeding, fasciotomy, and amputation in the entire cohort was 3.7%, 3.7%, and 0%, respectively. With strict adherence to a protocol for limb ischemia monitoring, a selective rather than prophylactic DPC strategy is safe and may obviate the risks of an additional arterial catheter.

在静脉体外膜氧合中常规使用远端灌注导管与选择性使用远端灌注导管的对比。
尽管目前的研究支持使用预防性远端灌注导管(DPC)来减少静脉体外膜肺氧合(VA ECMO)患者的肢体缺血,但不同研究监测肢体缺血的方法却不尽相同。我们在一个拥有完善肢体缺血监测方案的中心评估了选择性而非预防性 DPC 策略的安全性。如果有证据表明任何时候出现灌注不足,则有选择性地置入远端灌注导管,直至拔管。血管外科每天对所有患者进行随访,并持续进行区域饱和度监测。在接受 VA ECMO 支持的 188 名患者中,前期、延迟和无 DPC 患者的基线特征无明显差异。前期 DPC 患者的 30 天死亡率最高(前期 DPC 组为 56%,延迟 DPC 组为 19%,无 DPC 组为 22%,P < 0.001)。整个队列中大出血、筋膜切开术和截肢的发生率分别为 3.7%、3.7% 和 0%。在严格遵守肢体缺血监测方案的前提下,选择性而非预防性的 DPC 策略是安全的,并可避免额外的动脉导管风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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