A Prospective Cohort Study of Antimony Exposure and Cognitive Impairment in Older Adults - China, 2017-2021.

IF 4.3 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

中国疾病预防控制中心周报 Pub Date : 2024-06-07 DOI:10.46234/ccdcw2024.104

Yidan Qiu, Saisai Ji, Chen Chen, Jinhui Zhou, Jun Wang, Bing Wu, Yuan Wei, Fangyu Li, Xulin Zheng, Lanjing Xu, Zheng Zhang, Feng Zhao, Guangdi Chen, John S Ji, Yuebin Lyu, Shilu Tong, Xiaoming Shi

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Abstract

What is already known about this topic?: Antimony (Sb) has been identified as a new neurotoxicant that impacts neurological functions in animal studies. However, its effects on the human population remain unknown.

What is added by this report?: The study reveals that there is an association between exposure to Sb and a higher incidence of cognitive impairment in older adults. The dose-response curve demonstrates that the risk of cognitive impairment consistently increased with higher levels of Sb exposure without a discernible threshold.

What are the implications for public health practice?: Reducing exposure to Sb may have a beneficial effect in delaying or preventing the onset of cognitive impairment. This intervention has the potential to significantly decrease the disease burden associated with cognitive impairment, ultimately contributing to social development.

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2017-2021 年中国老年人锑暴露与认知障碍前瞻性队列研究》。

本专题的已知信息：锑（Sb）已被确定为一种新的神经毒物，在动物实验中会影响神经功能。本报告增加了哪些内容？本研究揭示了老年人接触锑与认知障碍发生率升高之间的关系。剂量-反应曲线表明，认知障碍的风险随着锑暴露水平的提高而持续增加，但没有明显的阈值：减少锑暴露可能对延缓或预防认知障碍的发生有益。这种干预措施有可能大大减轻与认知障碍相关的疾病负担，最终促进社会发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国疾病预防控制中心周报

CiteScore

5.90

自引率

0.00%

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