Successful endoscopic approach for peripheral neuroblastic tumors in children.

IF 1 4区医学 Q3 PEDIATRICS

Pediatrics International Pub Date : 2024-01-01 DOI:10.1111/ped.15754

Naonori Kawakubo, Junnosuke Maniwa, Keiko Irie, Akihiko Tamaki, Atsuhisa Fukuta, Ryota Souzaki, Satoshi Obata, Kouji Nagata, Toshiharu Matsuura, Tatsuro Tajiri

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引用次数: 0

Abstract

Background: Recently, reports of endoscopic approaches for neuroblastoma, ganglioneuroblastoma, and ganglioneuroma (peripheral neuroblastic tumor; PNTs) have been increasing. This study aimed to clarify the indications for endoscopic surgery for PNTs.

Methods: Pediatric patients who underwent endoscopic surgery for PNTs at our institution were included in this study. Image-defined risk factors (IDRFs) were analyzed using preoperative computed tomography (CT).

Results: Twenty-four patients underwent endoscopic surgery for PNTs. The diagnoses included neuroblastoma (n = 11), ganglioneuroma (n = 10), and ganglioneuroblastoma (n = 3). Regarding the tumor site, there were 18 cases of adrenal tumors, five cases of mediastinal tumors, and one case of retroperitoneal tumors. Image-defined risk factors were positive in eight cases (contacted with a renal vessel, n = 6; compression of principal bronchi, n = 2). Complete resection was accomplished in 21 cases (14 of 16 IDRF-negative cases and seven of eight IDRF-positive cases). All patients survived without recurrence during the follow-up period.

Conclusions: The CT findings of contact with renal vessels and compression of principal bronchi do not seem to be indicators of incomplete resection. An endoscopic approach to PNTs in pediatric patients is feasible with a good prognosis if patients are selected strictly.

查看原文本刊更多论文

成功采用内窥镜方法治疗儿童外周神经母细胞瘤。

背景：最近，有关神经母细胞瘤、神经节神经母细胞瘤和神经节细胞瘤（周围神经母细胞瘤，PNTs）的内镜手术报道越来越多。本研究旨在明确内镜手术治疗 PNTs 的适应症：本研究纳入了在我院接受内镜手术治疗 PNTs 的儿童患者。使用术前计算机断层扫描（CT）分析图像定义的风险因素（IDRF）：24名患者接受了内镜手术治疗PNTs。诊断包括神经母细胞瘤（11 例）、神经节细胞瘤（10 例）和神经节神经母细胞瘤（3 例）。就肿瘤部位而言，18 例为肾上腺肿瘤，5 例为纵隔肿瘤，1 例为腹膜后肿瘤。图像定义的危险因素呈阳性的有 8 例（与肾血管接触，6 例；压迫主支气管，2 例）。21例完成了完全切除（16例IDRF阴性病例中的14例和8例IDRF阳性病例中的7例）。所有患者在随访期间均无复发：与肾血管接触和压迫主支气管的 CT 发现似乎并不是切除不彻底的指标。如果严格选择患者，内镜方法治疗小儿 PNT 是可行的，且预后良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatrics International 医学-小儿科

CiteScore

2.00

自引率

7.10%

发文量

519

审稿时长

12 months

期刊介绍： Publishing articles of scientific excellence in pediatrics and child health delivery, Pediatrics International aims to encourage those involved in the research, practice and delivery of child health to share their experiences, ideas and achievements. Formerly Acta Paediatrica Japonica, the change in name in 1999 to Pediatrics International, reflects the Journal''s international status both in readership and contributions (approximately 45% of articles published are from non-Japanese authors). The Editors continue their strong commitment to the sharing of scientific information for the benefit of children everywhere. Pediatrics International opens the door to all authors throughout the world. Manuscripts are judged by two experts solely upon the basis of their contribution of original data, original ideas and their presentation.