Jessie R. Chung, Philip Shirk, Manjusha Gaglani, Manohar B. Mutnal, Mary Patricia Nowalk, Krissy Moehling Geffel, Stacey L. House, Tara Curley, Karen J. Wernli, Erika L. Kiniry, Emily T. Martin, Ivana A. Vaughn, Vel Murugan, Efrem S. Lim, Elie Saade, Kiran Faryar, Olivia L. Williams, Emmanuel B. Walter, Ashley M. Price, John R. Barnes, Juliana DaSilva, Rebecca Kondor, Sascha Ellington, Brendan Flannery
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Abstract
Background
The 2022–23 US influenza season peaked early in fall 2022.
Methods
Late-season influenza vaccine effectiveness (VE) against outpatient, laboratory-confirmed influenza was calculated among participants of the US Influenza VE Network using a test-negative design.
Results
Of 2561 participants enrolled from December 12, 2022 to April 30, 2023, 91 laboratory-confirmed influenza cases primarily had A(H1N1)pdm09 (6B.1A.5a.2a.1) or A(H3N2) (3C.2a1b.2a.2b). Overall, VE was 30% (95% confidence interval −9%, 54%); low late-season activity precluded estimation for most subgroups.
Conclusions
2022–23 late-season outpatient influenza VE was not statistically significant. Genomic characterization may improve the identification of influenza viruses that circulate postinfluenza peak.
期刊介绍:
Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases.
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