Evaluation of Remineralizing Capacity of Tricalcium Phosphate, Nano-Hydroxyapatite and Ozone Remineralizing Agents on the Artificial Carious Lesion.

Q3 Dentistry
Indian Journal of Dental Research Pub Date : 2024-01-01 Epub Date: 2024-06-20 DOI:10.4103/ijdr.ijdr_704_22
Shahzad Ali Shah, Mehak Sharma, Prabu Mahin Syed Ismail, Prashant Babaji, Azhar Mohammed, Bhavna Malik, Ananyo Mandal
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引用次数: 0

Abstract

Background: Dental caries is a dynamic process. By using therapeutic agents, early, noncavitated lesions and caries limited to the enamel can be stopped or even remineralized. For the remineralization of the initial carious lesion, many nonfluoridated remineralizing agents were investigated.

Objectives: An observational study to assess the remineralizing efficacy of tricalcium phosphate (TCP), nano-hydroxyapatite (nHAp) and ozone remineralizing agents on the artificial carious lesion.

Methodology: In this observational research, the artificial carious lesion was produced on extracted 40 premolar teeth. Later, remineralizing agents (Group A: nHAp, Group B: TCP, Group C: Ozone remineralizing agents, Group D: Control group (Deionized water) were used to remineralize demineralized teeth. Utilizing the Vickers Hardness Number, the level of demineralization and remineralization was assessed. Later these readings were statistically assessed using the Tukey's HSD (honestly significant difference) and ANOVA tests in SPSS version 21.0. The P value was set at 0.05 or less.

Results: After demineralization, there was a decrease in enamel microhardness values, with 32% in Group A, 26% in Group B, 22% in Group C, and 21% in Group D, respectively. From the baseline to demineralization, there was a statistically significant decrease in microhardness across all groups. After remineralization, Groups A, B, and C experienced an increase in microhardness while Group D experienced no changes. This showed that Group A had the highest remineralization percentage, followed by Group B and Group C.

Conclusion: nHAp and TCP had the greater remineralizing ability, which can be used to manage initial carious lesions.

评估磷酸三钙、纳米羟基磷灰石和臭氧再矿化剂对人工龋齿的再矿化能力
背景:龋齿是一个动态过程。通过使用治疗剂,可以阻止早期非龋坏和局限于釉质的龋坏,甚至使其再矿化。为了使初期龋损重新矿化,研究人员对许多非氟再矿化剂进行了调查:观察性研究:评估磷酸三钙(TCP)、纳米羟基磷灰石(nHAp)和臭氧再矿化剂对人工龋损的再矿化效果:在这项观察性研究中,在拔出的 40 颗前磨牙上制作人工龋损。随后,再矿化剂(A 组:nHAp;B 组:TCP;C 组:臭氧再矿化剂;D 组:TCP)和臭氧再矿化剂分别作用于人工龋损部位:臭氧再矿化剂,D 组:对照组(去离子水)用于再矿化脱矿牙齿。利用维氏硬度数评估脱矿化和再矿化的程度。之后,使用 SPSS 21.0 版的 Tukey's HSD(诚实显著差异)和方差分析测试对这些读数进行统计评估。结果:脱矿后,釉质微硬度值有所下降,A 组为 32%,B 组为 26%,C 组为 22%,D 组为 21%。从基线到脱矿,所有组的微硬度都有显著的统计学下降。再矿化后,A 组、B 组和 C 组的显微硬度有所增加,而 D 组则没有变化。结论:nHAp 和 TCP 的再矿化能力更强,可用于治疗初期龋损。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Indian Journal of Dental Research
Indian Journal of Dental Research Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
80
审稿时长
38 weeks
期刊介绍: Indian Journal of Dental Research (IJDR) is the official publication of the Indian Society for Dental Research (ISDR), India section of the International Association for Dental Research (IADR), published quarterly. IJDR publishes scientific papers on well designed and controlled original research involving orodental sciences. Papers may also include reports on unusual and interesting case presentations and invited review papers on significant topics.
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