Ecological, beneficial, and pathogenic functions of the Type 9 Secretion System

IF 5.7 2区 生物学
Sofia T. Rocha, Dhara D. Shah, Abhishek Shrivastava
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引用次数: 0

Abstract

The recently discovered Type 9 Secretion System (T9SS) is present in bacteria of the Fibrobacteres–Bacteroidetes–Chlorobi superphylum, which are key constituents of diverse microbiomes. T9SS is instrumental in the extracellular secretion of over 270,000 proteins, including peptidases, sugar hydrolases, metal ion-binding proteins, and metalloenzymes. These proteins are essential for the interaction of bacteria with their environment. This mini-review explores the extensive array of proteins secreted by the T9SS. It highlights the diverse functions of these proteins, emphasizing their roles in pathogenesis, bacterial interactions, host colonization, and the overall health of the ecosystems inhabited by T9SS-containing bacteria.

Abstract Image

9 型分泌系统的生态、有益和致病功能。
最近发现的 9 型分泌系统(T9SS)存在于纤维细菌-类杆菌-绿生物超门的细菌中,它们是各种微生物群的关键组成部分。T9SS 在超过 27 万种蛋白质的胞外分泌中起着重要作用,其中包括肽酶、糖水解酶、金属离子结合蛋白和金属酶。这些蛋白质对于细菌与环境的相互作用至关重要。这篇微型综述探讨了 T9SS 分泌的大量蛋白质。它重点介绍了这些蛋白质的各种功能,强调了它们在致病机理、细菌相互作用、宿主定殖以及含 T9SS 细菌所居住的生态系统的整体健康中的作用。
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来源期刊
Microbial Biotechnology
Microbial Biotechnology Immunology and Microbiology-Applied Microbiology and Biotechnology
CiteScore
11.20
自引率
3.50%
发文量
162
审稿时长
1 months
期刊介绍: Microbial Biotechnology publishes papers of original research reporting significant advances in any aspect of microbial applications, including, but not limited to biotechnologies related to: Green chemistry; Primary metabolites; Food, beverages and supplements; Secondary metabolites and natural products; Pharmaceuticals; Diagnostics; Agriculture; Bioenergy; Biomining, including oil recovery and processing; Bioremediation; Biopolymers, biomaterials; Bionanotechnology; Biosurfactants and bioemulsifiers; Compatible solutes and bioprotectants; Biosensors, monitoring systems, quantitative microbial risk assessment; Technology development; Protein engineering; Functional genomics; Metabolic engineering; Metabolic design; Systems analysis, modelling; Process engineering; Biologically-based analytical methods; Microbially-based strategies in public health; Microbially-based strategies to influence global processes
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