Revision Rates After Single-Level Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy and Fusion: An Observational Study With 5-Year Minimum Follow-Up.

IF 2.6 2区 医学 Q2 CLINICAL NEUROLOGY
Spine Pub Date : 2025-01-01 Epub Date: 2024-06-25 DOI:10.1097/BRS.0000000000005079
Adam M Gordon, Faisal R Elali, Ahmed Saleh
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引用次数: 0

Abstract

Study design: A retrospective case-control study.

Objectives: This study aimed to compare rates and risk factors for all-cause 5-year revisions for patients undergoing primary single-level cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF).

Summary of background data: Prospective studies have compared patient-reported outcomes, adjacent segment degeneration, and long-term revisions between CDA and ACDF. Despite these high-level evidence studies, well-powered, large investigations have not been adequately reported.

Patients and methods: A nationwide database was queried for patients undergoing primary single-level CDA or ACDF for degenerative cervical spine pathology. Further inclusion criteria consisted of patients having a minimum 5-year follow-up. Patients undergoing CDA were in a 1:5 ratio matched to patients undergoing ACDF by age, sex, comorbidities, and overall Elixhauser comorbidity index (ECI). Objectives were to compare the rates and risk factors of all-cause 5-year revisions for those undergoing single-level CDA versus ACDF. Multivariate logistic regression models computed the odds ratios (ORs) of revisions within 5 years. P values of less than 0.001 were significant.

Results: A total of 32,953 patients underwent single-level CDA (N=5,640) or ACDF (N=27,313) with a 5-year minimum follow-up. The incidence of all-cause revisions within 5 years was 1.24% for CDA and 9.23% for ACDF ( P <0.001). After adjustment, patients undergoing single-level ACDF had significantly higher odds of all-cause revisions within 5 years (OR: 8.09; P <0.0001). Additional patient-specific factors associated with revisions were a history of reported drug abuse (OR: 1.51; P <0.0001), depression (OR: 1.23; P <0.0001), cardiac arrhythmias (OR: 1.21; P =0.0008), hypertension (OR: 1.20; P =0.0006), and tobacco use (OR: 1.18; P =0.0003).

Conclusions: In this study of nearly 33,000 single-level cervical spine surgeries with minimum 5-year follow-up, all-cause revision rates were significantly lower for patients undergoing CDA. Surgeons may use this data to counsel patients regarding 5-year revisions following single-level CDA or ACDF.

Level of evidence: III.

单层颈椎间盘关节置换术与颈椎前路椎间盘切除融合术后的复发率:最少随访 5 年的观察性研究。
研究设计研究目的:回顾性病例对照研究:本研究旨在比较接受初级单水平颈椎间盘关节置换术(CDA)与前路颈椎椎间盘切除融合术(ACDF)的患者5年全因翻修率和风险因素:前瞻性研究比较了CDA和ACDF的患者报告结果、邻近节段退变和长期翻修情况。尽管有这些高水平的证据研究,但尚未充分报告有充分证据支持的大型调查:在全国范围内的数据库中查询了因颈椎退行性病变而接受初级单水平CDA或ACDF手术的患者。进一步的纳入标准包括随访至少5年的患者。根据年龄、性别、合并症和总体埃利克豪斯合并症指数(ECI),接受CDA的患者与接受ACDF的患者按1:5的比例进行配对。目的是比较接受单层 CDA 和 ACDF 治疗的患者 5 年全因复发率和风险因素。多变量逻辑回归模型计算了5年内翻修的几率比(OR)。P值小于0.001为显著:共有 32953 名患者接受了单层 CDA(N=5640)或 ACDF(N=27313)手术,随访时间最短为 5 年。5年内所有原因的翻修发生率,CDA为1.24%,ACDF为9.23%(PConclusions:在这项对近 33,000 例单层次颈椎手术进行至少 5 年随访的研究中,接受 CDA 的患者因各种原因导致的翻修率明显较低。外科医生可利用这些数据就单层次 CDA 或 ACDF 术后 5 年翻修问题向患者提供咨询:证据等级:III。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Spine
Spine 医学-临床神经学
CiteScore
5.90
自引率
6.70%
发文量
361
审稿时长
6.0 months
期刊介绍: Lippincott Williams & Wilkins is a leading international publisher of professional health information for physicians, nurses, specialized clinicians and students. For a complete listing of titles currently published by Lippincott Williams & Wilkins and detailed information about print, online, and other offerings, please visit the LWW Online Store. Recognized internationally as the leading journal in its field, Spine is an international, peer-reviewed, bi-weekly periodical that considers for publication original articles in the field of Spine. It is the leading subspecialty journal for the treatment of spinal disorders. Only original papers are considered for publication with the understanding that they are contributed solely to Spine. The Journal does not publish articles reporting material that has been reported at length elsewhere.
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