Effect of coating time on the formation of coating layer and degradation behavior of hydroxyapatite coated ZK60 alloy.

IF 3.1 4区 医学 Q2 BIOPHYSICS
Le Van Hai, Do Nhu Ngoc, Pham Mai Khanh, Le Van Tuan, Vu Nhat Dinh, Nguyen Viet Nam
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引用次数: 0

Abstract

Objectives: This study aims to investigate the effect of coating time on the formation of hydroxyapatite (HA) coating layer on ZK60 substrate and understand the biodegradation behavior of the coated alloy for biodegradable implant applications.

Methods: Biodegradable ZK60 alloy was coated by HA layer for different times of 0.5, 1, 2, and 4 h by chemical conversion method. After coating, all the coated specimens were used for immersion test in Hanks' solution to understand the effect of coating time on the degradation behavior of the alloy. The degradation rate of the coated alloy was evaluated by Mg2+ ion quantification and pH change during immersion test. The microstructure of the coating layer was examined by scanning electron microscope (SEM) equipped with an energy-dispersive X-ray spectroscopy (EDS) before and after immersion to understand the degradation behavior of the coated alloy.

Results: HA coating layers were formed successfully on surface of ZK60 specimens after 0.5, 1, 2, and 4 h with different microstructure. Optimal coating quality was observed at 1 or 2 h, characterized by well-formed and uniform HA layers. However, extending the coating duration to 4 h led to the formation of cracks within the HA layer, accompanied by Mg(OH)2. Specimens coated for 1 and 2 h exhibited the lowest degradation rates, while specimens coated for 0.5 and 4 h showed the highest degradation rates. Furthermore, analysis of degradation products revealed the predominance of calcium phosphates formed on the surface of specimens coated for 1 and 2 h. Conversely, specimens coated for 0.5 and 4 h exhibited Mg(OH)2 as the primary degradation product, suggesting a less effective corrosion barrier under these conditions.

Conclusion: The HA layer formed after 2 h demonstrated as the most effective coating layer for enhancing the corrosion resistance of the ZK60 alloy for biomedical applications.

涂层时间对羟基磷灰石涂层 ZK60 合金的涂层形成和降解行为的影响。
研究目的本研究旨在探讨涂覆时间对羟基磷灰石(HA)涂覆层在 ZK60 基底上形成的影响,并了解涂覆合金在生物降解植入物应用中的生物降解行为:方法:采用化学转化法对可生物降解的 ZK60 合金进行 0.5、1、2 和 4 h 不同时间的 HA 涂层处理。涂覆后,所有涂覆试样均在 Hanks 溶液中进行浸泡试验,以了解涂覆时间对合金降解行为的影响。在浸泡试验过程中,通过 Mg2+ 离子定量和 pH 值变化评估了涂层合金的降解率。用配备了能量色散 X 射线光谱仪(EDS)的扫描电子显微镜(SEM)观察了浸泡前后涂层的微观结构,以了解涂层合金的降解行为:0.5、1、2 和 4 小时后,不同微观结构的 ZK60 试样表面成功形成了 HA 涂层。在 1 或 2 小时内观察到最佳涂层质量,其特征是形成良好且均匀的 HA 涂层。然而,将涂层时间延长至 4 小时后,HA 层内会形成裂缝,并伴有 Mg(OH)2。涂覆时间为 1 和 2 小时的试样降解率最低,而涂覆时间为 0.5 和 4 小时的试样降解率最高。此外,对降解产物的分析表明,涂覆 1 和 2 小时的试样表面形成的主要是磷酸钙。相反,涂覆 0.5 和 4 小时的试样的主要降解产物是 Mg(OH)2,这表明在这些条件下的腐蚀屏障效果较差:结论:在生物医学应用中,2 小时后形成的 HA 层是增强 ZK60 合金耐腐蚀性最有效的涂层。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Applied Biomaterials & Functional Materials
Journal of Applied Biomaterials & Functional Materials BIOPHYSICS-ENGINEERING, BIOMEDICAL
CiteScore
4.40
自引率
4.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: The Journal of Applied Biomaterials & Functional Materials (JABFM) is an open access, peer-reviewed, international journal considering the publication of original contributions, reviews and editorials dealing with clinical and laboratory investigations in the fast growing field of biomaterial sciences and functional materials. The areas covered by the journal will include: • Biomaterials / Materials for biomedical applications • Functional materials • Hybrid and composite materials • Soft materials • Hydrogels • Nanomaterials • Gene delivery • Nonodevices • Metamaterials • Active coatings • Surface functionalization • Tissue engineering • Cell delivery/cell encapsulation systems • 3D printing materials • Material characterization • Biomechanics
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