Adverse Effects Related to Paediatric Influenza Vaccination and Its Influence on Vaccination Acceptability. The FLUTETRA Study: A Survey Conducted in the Region of Murcia, Spain

IF 4.3 4区 医学 Q1 INFECTIOUS DISEASES
Matilde Zornoza Moreno, Jaime Jesús Pérez Martín, María Cruz Gómez Moreno, María del Carmen Valcárcel Gómez, Marta Pérez Martínez, Francisca Isabel Tornel Miñarro
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Abstract

Background

During the 2022–23 season, three autonomous communities recommended influenza vaccination for all children between 6 and 59 months. The objective is to evaluate the adverse effects associated with the administered influenza vaccines in the Region of Murcia, as well as their influence on the recommendation of the same to acquaintances or repetition in future seasons.

Material and Methods

Cross-sectional descriptive study with an online questionnaire sent to the parents of vaccinated minors of 6–23 months of age receiving inactivated intramuscular vaccine (IIV) or 24–59 months of age receiving live-attenuated intranasal vaccine (LAIV).

Results

Among 4971 surveys received, the most common adverse effect for LAIV and IIV was runny nose (40.90%) and local pain (31.94%), respectively. Sixty percent of adverse effects lasted ≤ 1 day, and around 10% lasted ≥ 3 days. The interference of adverse effects with the minor's daily life was very infrequent (3.32%), as was the need for visiting the medical office (2.68%). Overall, 96.44% of parents would recommend influenza vaccination to friends and relatives after the experience. Only 3.56% would not recommend it, while 1.68% would not vaccinate their child against influenza again. The most frequently cited reason being adverse effects.

Conclusions

Our study shows the safety of influenza vaccines. Despite the low impact of adverse effects, they influence some parents in their intention to continue vaccinating or recommending it to acquaintances, which remarks the need to reinforce the information given to parents so that this fact does not influence decision-making.

Abstract Image

与儿童流感疫苗接种有关的不良反应及其对疫苗接种可接受性的影响。FLUTETRA 研究:在西班牙穆尔西亚地区开展的一项调查
背景 2022-23 年流感季节期间,三个自治区建议所有 6 至 59 个月的儿童接种流感疫苗。研究的目的是评估穆尔西亚地区接种流感疫苗的不良反应,以及这些不良反应对向熟人推荐接种流感疫苗或在未来季节重复接种流感疫苗的影响。 材料与方法 横向描述性研究,向 6-23 个月龄接种肌肉注射灭活疫苗(IIV)或 24-59 个月龄接种鼻内减毒活疫苗(LAIV)的未成年人的父母发送在线问卷。 结果 在收到的 4971 份调查中,LAIV 和 IIV 最常见的不良反应分别是流鼻涕(40.90%)和局部疼痛(31.94%)。60%的不良反应持续时间不超过 1 天,约 10%持续时间超过 3 天。不良反应对未成年人日常生活造成干扰的情况很少(3.32%),需要到医务室就诊的情况也很少(2.68%)。总体而言,96.44% 的家长在体验后会向亲友推荐流感疫苗接种。只有 3.56% 的家长不会推荐,1.68% 的家长不会再给孩子接种流感疫苗。最常见的原因是不良反应。 结论 我们的研究表明流感疫苗是安全的。尽管不良反应的影响较小,但它们影响了一些家长继续接种或向熟人推荐的意向,这说明有必要加强向家长提供的信息,以免这一事实影响决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.50%
发文量
120
审稿时长
6-12 weeks
期刊介绍: Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases. Influenza and Other Respiratory Viruses is an Open Access journal. Copyright on any research article published by Influenza and Other Respiratory Viruses is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified.
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