Evaluation of the quality of platelet concentrates obtained in a Peruvian hospital.

IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL

Medwave Pub Date : 2024-06-21 DOI:10.5867/medwave.2024.05.2776

Jair Huamani-Chacchi, Fernando Soncco-Llulluy, Jaime Rosales-Rimache

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引用次数: 0

Abstract

Introduction: Platelet concentrates are blood products obtained from donor's blood, and their conservation must be subject to a strict quality control process to guarantee a safe and high-performance product in treating diseases that require their use.

Methods: We designed a cross-sectional study to determine the total compliance rate in platelet concentrates obtained in the blood bank of the Cayetano Heredia Hospital in Lima during November and December of 2019. The Buffy method Coat obtained the platelet concentrates, and parameters such as platelet count and residual leukocytes, pH, and swirling effect were evaluated according to the National Hemotherapy and Blood Bank Program criteria.

Results: The platelet count had a mean of 6.66 ± 3.94 x 10¹⁰/µL, the platelet concentrates had a mean of 56.30 ± 6.22 mL, and all, without exception, had the presence of the Swirling phenomenon. The pH had a mean of 7.64 ± 0.15, while the leukocyte count had a mean of 4.22 ± 3.51 x 10⁷/µL. Regarding compliance by the parameters evaluated, it was evident that the platelet and leukocyte count had moderate compliance rates of 43.6% and 24.1%, while the pH and swirling effect had rates of 100% in both cases. The total compliance rate was 54.9% (95% confidence interval: 46.0 to 63.5).

Conclusions: The compliance rate of platelet concentrates is moderate, and it is necessary to implement a process of continuous quality improvement in the blood bank.

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评估在秘鲁一家医院获得的血小板浓缩物的质量。

引言血小板浓缩物是从献血者血液中提取的血液制品，其保存必须经过严格的质量控制过程，以保证在治疗需要使用血小板浓缩物的疾病时获得安全、高效的产品：我们设计了一项横断面研究，以确定 2019 年 11 月和 12 月期间在利马卡耶塔诺-埃雷迪亚医院血库获得的血小板浓缩物的总合格率。根据国家血液治疗和血库计划标准，采用巴菲法 Coat 获得血小板浓缩液，并对血小板计数和残留白细胞、pH 值和漩涡效应等参数进行评估：血小板计数的平均值为 6.66 ± 3.94 x 10¹⁰/µL，血小板浓缩物的平均值为 56.30 ± 6.22 mL，无一例外都出现了漩涡现象。pH 值平均为 7.64 ± 0.15，白细胞计数平均为 4.22 ± 3.51 x 10⁷/µL。关于评估参数的符合率，血小板和白细胞计数的符合率分别为 43.6% 和 24.1%，属于中等水平，而 pH 值和漩涡效应的符合率均为 100%。总符合率为 54.9%（95% 置信区间：46.0 至 63.5）：血小板浓缩物的合格率一般，血库有必要实施持续质量改进流程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medwave MEDICINE, GENERAL & INTERNAL-

CiteScore

2.60

自引率

8.30%

发文量

审稿时长

12 weeks

期刊介绍： Medwave is a peer-reviewed, biomedical and public health journal. Since its foundation in 2001 (Volume 1) it has always been an online only, open access publication that does not charge subscription or reader fees. Since January 2011 (Volume 11, Number 1), all articles are peer-reviewed. Without losing sight of the importance of evidence-based approach and methodological soundness, the journal accepts for publication articles that focus on providing updates for clinical practice, review and analysis articles on topics such as ethics, public health and health policy; clinical, social and economic health determinants; clinical and health research findings from all of the major disciplines of medicine, medical science and public health. The journal does not publish basic science manuscripts or experiments conducted on animals. Until March 2013, Medwave was publishing 11-12 numbers a year. Each issue would be posted on the homepage on day 1 of each month, except for Chile’s summer holiday when the issue would cover two months. Starting from April 2013, Medwave adopted the continuous mode of publication, which means that the copyedited accepted articles are posted on the journal’s homepage as they are ready. They are then collated in the respective issue and included in the Past Issues section.