Antioxidant potential and polyphenol content in different parts of Graptophyllum pictum extracts.

IF 1.4 Q3 Pharmacology, Toxicology and Pharmaceutics
Feda Anisah Makkiyah, Eldiza Puji Rahmi, Rini Anggi Arista, Nelly Marliani, Waras Nurcholis
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引用次数: 0

Abstract

The antioxidant potential of Graptophyllum pictum (wungu leaves), an indigenous shrub plant extensively used in traditional medicine in Indonesia, was investigated in this study. The research focused on a comprehensive evaluation of total phenolic content (TPC), total flavonoid content (TFC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric-reducing antioxidant power (FRAP) across various plant parts, including roots, stems, and flowers, which had been underexplored in prior studies. The ethanol extract derived from wungu flowers and leaves demonstrated notable antioxidant potential, characterized by elevated TPC (12.22 ± 0.31 mg GAE/g DW) and FRAP (37.73 ± 1.08 μmol TEAC/g DW) in the ethanol extract of wungu flowers. Similarly, the ethanol extract of wungu leaves showcased a substantial TFC (2.31 ± 0.18 mg QE/g DW) and DPPH (1.12 ± 0.05 μmol TEAC/g DW), surpassing other parts of the wungu plant in the same or different extracts. These findings suggested that ethanol extracts were a promising foundation for herbal medicines with antioxidant properties, highlighting their potential applications in plant breeding programs. Furthermore, the correlation data underscored the significance of the ethyl acetate and ethanol extracts, revealing a robust correlation between TPC, TFC, and FRAP compared to the n-hexane extract.

虎皮兰不同部位提取物的抗氧化潜力和多酚含量。
本研究调查了印度尼西亚一种广泛用于传统医学的本地灌木植物--Graptophyllum pictum(翁谷叶)的抗氧化潜力。研究的重点是全面评估植物各部分(包括根、茎和花)的总酚含量(TPC)、总黄酮含量(TFC)、2,2-二苯基-1-苦基肼(DPPH)和铁还原抗氧化力(FRAP),而在之前的研究中对这些部分的研究还不够深入。翁谷花和叶的乙醇提取物具有显著的抗氧化潜力,其特点是翁谷花乙醇提取物中的 TPC(12.22 ± 0.31 mg GAE/g DW)和 FRAP(37.73 ± 1.08 μmol TEAC/g DW)均有所提高。同样,在相同或不同萃取物中,芒果叶乙醇萃取物的TFC(2.31 ± 0.18 mg QE/g DW)和DPPH(1.12 ± 0.05 μmol TEAC/g DW)含量也很高,超过了芒果植物的其他部分。这些研究结果表明,乙醇提取物是具有抗氧化特性的草药的基础,突出了其在植物育种计划中的潜在应用。此外,相关数据强调了乙酸乙酯和乙醇提取物的重要性,与正己烷提取物相比,乙醇提取物中的 TPC、TFC 和 FRAP 之间具有很强的相关性。
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来源期刊
CiteScore
2.00
自引率
7.10%
发文量
44
审稿时长
20 weeks
期刊介绍: Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is an Official Publication of Society of Pharmaceutical Education & Research™. It is an international journal published Quarterly. Journal of Advanced Pharmaceutical Technology & Research (JAPTR) is available in online and print version. It is a peer reviewed journal aiming to communicate high quality original research work, reviews, short communications, case report, Ethics Forum, Education Forum and Letter to editor that contribute significantly to further the scientific knowledge related to the field of Pharmacy i.e. Pharmaceutics, Pharmacology, Pharmacognosy, Pharmaceutical Chemistry. Articles with timely interest and newer research concepts will be given more preference.
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