Navigating the Uncharted: A Rare Case of Ocular Flutter and Intermittent Jaw Movements in a Case of Chronic Lymphoid Leukemia.

IF 1.9 4区 医学 Q3 CLINICAL NEUROLOGY
Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-20 DOI:10.4103/aian.aian_22_24
Kunal Arora, Amit S Singh, Rajeev Bedi, Ketan Dang, Arunjeet Kaur
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引用次数: 0

Abstract

Although chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world, neurologic complications arising from direct leukemic involvement of the nervous system are reported in only 1% of patients with CLL. Ocular involvement in CLL, direct or indirect, is less known and exceptionally rare. This case involves a 63-year-old female with CLL undergoing chemotherapy for a year, who recently presented with unusual eye movements in the horizontal plane (ocular flutter), resting and intentional tremors in the right upper and lower limbs, and intermittent jaw movements. With no established protocol for CLL with central nervous system involvement, collecting case data becomes crucial for determining optimal treatment and diagnostic approaches early on.

探索未知领域:慢性淋巴细胞白血病患者眼球震颤和间歇性下颌运动的罕见病例。
摘要:虽然慢性淋巴细胞白血病(CLL)是西方世界最常见的白血病,但只有1%的CLL患者因白血病直接累及神经系统而出现神经系统并发症。CLL直接或间接累及眼部的病例鲜为人知,而且异常罕见。本病例涉及一名接受化疗一年的 63 岁女性 CLL 患者,她最近出现了眼球在水平面上的异常运动(眼球跳动)、右上肢和右下肢的静止性和有意性震颤以及间歇性下颌运动。由于没有针对中枢神经系统受累的 CLL 的既定方案,因此收集病例数据对于在早期确定最佳治疗和诊断方法至关重要。
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来源期刊
Annals of Indian Academy of Neurology
Annals of Indian Academy of Neurology Nervous System Diseases-
CiteScore
2.20
自引率
11.80%
发文量
293
审稿时长
29 weeks
期刊介绍: The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.
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