Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus.

IF 2.5 4区生物学 Q3 MICROBIOLOGY

Future microbiology Pub Date : 2024-08-12 Epub Date: 2024-06-20 DOI:10.1080/17460913.2024.2357994

Jing Luo, Rui Xie, Chongxi Bao, Jinyan Lin, Yang Xu, Xuexin Yan, Zhen Yang, Li Feng, Jianing Wu, Dan Chen, Zaiqing He, Jinliang Kong

{"title":"Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus.","authors":"Jing Luo, Rui Xie, Chongxi Bao, Jinyan Lin, Yang Xu, Xuexin Yan, Zhen Yang, Li Feng, Jianing Wu, Dan Chen, Zaiqing He, Jinliang Kong","doi":"10.1080/17460913.2024.2357994","DOIUrl":null,"url":null,"abstract":"Aim: To investigate the impact of human herpes virus (HHV) carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients.Methods: Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into HHV (n = 15) and non-HHV (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored.Results: Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between Prevotella, Porphyromonas, Streptococcus and basophil/eosinophil percentages.Conclusion: HHV carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to HHV reactivation in outpatient lung infection patients.","PeriodicalId":12773,"journal":{"name":"Future microbiology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11323855/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/17460913.2024.2357994","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/20 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Aim: To investigate the impact of human herpes virus (HHV) carriage on lung microbiota, and its correlation with clinical features and laboratory indicators in patients.Methods: Retrospective analysis was conducted on 30 outpatient lung infection cases, which were divided into HHV (n = 15) and non-HHV (n = 15) groups. mNGS detected microbial composition. Microbial diversity and abundance were tested using Shannon and Chao1 indices. Their relationship with laboratory indicators were explored.Results: Significant differences in microbial abundance and distribution were found between two groups (p < 0.05). Moreover, HHV group showed negative correlations (p < 0.05) between Prevotella, Porphyromonas, Streptococcus and basophil/eosinophil percentages.Conclusion: HHV carriage impacts lung microbiota, emphasizing the need for clinicians to pay attention to HHV reactivation in outpatient lung infection patients.

查看原文本刊更多论文

分析携带人类疱疹病毒患者的肺部微生态学和临床特征。

目的：研究人类疱疹病毒（HHV）携带对肺部微生物群的影响及其与患者临床特征和实验室指标的相关性。方法：对 30 名门诊肺部患者进行回顾性分析：对 30 例门诊肺部感染病例进行回顾性分析，分为 HHV 组（15 例）和非 HHV 组（15 例）。使用香农指数和 Chao1 指数检测了微生物的多样性和丰度。探讨了它们与实验室指标的关系。结果发现两组之间微生物丰度和分布存在显著差异（p Prevotella、卟啉单胞菌、链球菌和嗜碱性粒细胞/嗜酸性粒细胞百分比）。结论HHV携带会影响肺部微生物群，因此临床医生需要关注门诊肺部感染患者的HHV再激活情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Future microbiology 生物-微生物学

CiteScore

4.90

自引率

3.20%

发文量

134

审稿时长

6-12 weeks

期刊介绍： Future Microbiology delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this increasingly important and vast area of research.