Unprovoked venous thromboembolism recurrence and arterial embolism revealing lung cancer: a case report.

IF 2.6 4区 医学 Q2 HEMATOLOGY
Maria-Cristina Glodeanu, Victoria Mutruc, Camelia-Maria Apetrei, Manuela Ursaru, Laurentiu Sorodoc, Catalina Lionte
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Abstract

The link between venous thromboembolism (VTE) and cancer is well known. VTE could be the initial sign of an occult malignancy. There are more diagnoses of cancer after an unprovoked VTE compared to a provoked VTE, with a reported prevalence between 4.5% and 5.6% over 12 months, within the first 6 months of VTE diagnosis. There are no recommended guidelines and scores yet adopted in clinical practice, but many studies support occult cancer screening in unprovoked VTE patients. We report the case of a patient with a history of unprovoked pulmonary embolism (PE) diagnosed with bronchopulmonary neoplasm in an advanced stage one year after the thromboembolic event. When the cancer was first diagnosed, the patient's condition was already serious, being too late for the adoption of measures meant to decrease the risk of mortality and increase the duration of survival. We wanted to emphasize the importance of occult cancer screening in patients with unprovoked VTE and the fact that early cancer diagnosis reduces the risk of cancer progression, decreasing mortality and morbidity related to it.

揭示肺癌的无诱因静脉血栓栓塞复发和动脉栓塞:病例报告。
静脉血栓栓塞症(VTE)与癌症之间的联系众所周知。VTE 可能是隐匿性恶性肿瘤的最初征兆。与诱发的 VTE 相比,无诱因的 VTE 后诊断出癌症的更多,据报道,在 VTE 诊断后的前 6 个月内,12 个月内的发病率在 4.5% 到 5.6% 之间。临床实践中尚未采用推荐的指南和评分,但许多研究支持对无诱因 VTE 患者进行隐匿性癌症筛查。我们报告了一例无诱因肺栓塞(PE)患者的病例,该患者在血栓栓塞事件发生一年后被诊断为支气管肺肿瘤晚期。首次诊断出癌症时,患者的病情已经很严重,采取旨在降低死亡风险和延长生存期的措施为时已晚。我们希望强调对无诱因 VTE 患者进行隐匿性癌症筛查的重要性,以及早期癌症诊断可降低癌症恶化的风险、降低死亡率和发病率的事实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Thrombosis Journal
Thrombosis Journal Medicine-Hematology
CiteScore
3.80
自引率
3.20%
发文量
69
审稿时长
16 weeks
期刊介绍: Thrombosis Journal is an open-access journal that publishes original articles on aspects of clinical and basic research, new methodology, case reports and reviews in the areas of thrombosis. Topics of particular interest include the diagnosis of arterial and venous thrombosis, new antithrombotic treatments, new developments in the understanding, diagnosis and treatments of atherosclerotic vessel disease, relations between haemostasis and vascular disease, hypertension, diabetes, immunology and obesity.
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