Interplay between diabetes mellitus and atopic dermatitis

IF 3.5 3区 医学 Q1 DERMATOLOGY
Dongyun Lei, Jiechen Zhang, Tingting Zhu, Litao Zhang, Mao-Qiang Man
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Abstract

Inflammatory dermatoses such as atopic dermatitis (AD) have long been linked to the pathogenesis of diabetes mellitus. Indeed, numerous studies show an increased risk of diabetes mellitus in individuals with AD although lower prevalence of diabetes mellitus is also observed in few studies. Though the underlying mechanisms accounting for the reciprocal influence between these two conditions are still unclear, the complex interplay between diabetes mellitus and AD is attributable, in part, to genetic and environmental factors, cytokines, epidermal dysfunction, as well as drugs used for the treatment of AD. Proper management of one condition can mitigate the other condition. In this review, we summarize the evidence of the interaction between diabetes mellitus and AD, and discuss the possible underlying mechanisms by which these two conditions influence each other.

糖尿病与特应性皮炎之间的相互作用。
长期以来,特应性皮炎(AD)等炎症性皮肤病一直与糖尿病的发病机制有关。事实上,许多研究表明,特应性皮炎患者罹患糖尿病的风险增加,但也有少数研究观察到特应性皮炎患者的糖尿病患病率较低。虽然这两种疾病之间相互影响的内在机制尚不清楚,但糖尿病和注意力缺失症之间复杂的相互作用部分归因于遗传和环境因素、细胞因子、表皮功能障碍以及用于治疗注意力缺失症的药物。对其中一种病症的适当治疗可减轻另一种病症。在这篇综述中,我们总结了糖尿病和注意力缺失症之间相互作用的证据,并讨论了这两种疾病相互影响的可能内在机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Experimental Dermatology
Experimental Dermatology 医学-皮肤病学
CiteScore
6.70
自引率
5.60%
发文量
201
审稿时长
2 months
期刊介绍: Experimental Dermatology provides a vehicle for the rapid publication of innovative and definitive reports, letters to the editor and review articles covering all aspects of experimental dermatology. Preference is given to papers of immediate importance to other investigators, either by virtue of their new methodology, experimental data or new ideas. The essential criteria for publication are clarity, experimental soundness and novelty. Letters to the editor related to published reports may also be accepted, provided that they are short and scientifically relevant to the reports mentioned, in order to provide a continuing forum for discussion. Review articles represent a state-of-the-art overview and are invited by the editors.
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