Long-Term Clinical and Radiographic Outcomes of Meniscus Allograft Transplant.

IF 2.9 2区 医学 Q1 ORTHOPEDICS
Andrew R Phillips, Erik C Haneberg, Stephanie A Boden, Adam B Yanke, Brian J Cole
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Abstract

Purpose of review: To reduce pain, improve function and possibly mitigate the risk for development of osteoarthritis in patients with functionally deficient meniscus pathology, meniscal allograft transplantation (MAT) can be used to restore native joint biomechanics and increase knee joint longevity. This review explores the senior author's preferred bridge-in-slot technique and recently published long-term clinical and radiographic outcomes following MAT.

Recent findings: Recent literature demonstrates MAT to be a safe and largely successful procedure for patients with functional meniscus deficiency. A majority of patients reach established minimal clinically important difference (MCID) values. Graft survivorship is approximately 80% at 10 years, significantly delaying and in some cases, preventing the need for future joint reconstruction procedures in these young patients. Return to sport rates are over 70%, revealing meniscal allografts can withstand high impact activities. Cartilage damage at the time of MAT increases the risk for graft and clinical failure, though this may be mitigated with a concomitant cartilage restoration procedure. Meniscal allograft transplantation can provide a durable and effective long-term solution to meniscal deficiency in symptomatic patients who wish to decrease the risk of symptomatic progression and possibly further osteoarthritis and continue activities of daily life and sports with less pain and more function. By restoring more normal joint biomechanics, MAT can mitigate the potential need for future knee arthroplasty in this young active patient population.

半月板同种异体移植的长期临床和影像学结果
综述目的:半月板同种异体移植(MAT)可用于恢复原始关节生物力学,延长膝关节寿命,从而减轻半月板功能缺陷患者的疼痛,改善其功能,并降低其发展为骨关节炎的风险。这篇综述探讨了资深作者首选的槽中桥技术以及最近发表的半月板异位移植术后的长期临床和影像学结果:最新研究结果:最近的文献表明,MAT 对功能性半月板缺损患者来说是一种安全且基本成功的手术。大多数患者都能达到既定的最小临床重要差异(MCID)值。移植后10年的存活率约为80%,大大推迟了这些年轻患者今后接受关节重建手术的时间,在某些情况下甚至避免了这种需要。运动恢复率超过 70%,这表明半月板异体移植可以承受高冲击力的活动。半月板异体移植时软骨受损会增加移植和临床失败的风险,但同时进行软骨修复手术可以减轻这种风险。对于有症状的患者,半月板同种异体移植可为半月板缺损提供一种持久有效的长期解决方案,这些患者希望降低症状发展的风险,并可能进一步发展骨关节炎,同时希望在减少疼痛和增强功能的情况下继续日常生活和运动。通过恢复更正常的关节生物力学,半月板修复术可减轻这一年轻活跃患者群体对未来膝关节置换术的潜在需求。
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来源期刊
CiteScore
7.50
自引率
2.40%
发文量
64
期刊介绍: This journal intends to review the most significant recent developments in the field of musculoskeletal medicine. By providing clear, insightful, balanced contributions by expert world-renowned authors, the journal aims to serve all those involved in the diagnosis, treatment, management, and prevention of musculoskeletal-related conditions. We accomplish this aim by appointing authorities to serve as Section Editors in key subject areas, such as rehabilitation of the knee and hip, sports medicine, trauma, pediatrics, health policy, customization in arthroplasty, and rheumatology. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 20 diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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