Evaluation of baghdadite (Ca3ZrSi2O9) cements for the application as novel endodontic filling materials

IF 4.6 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Dental Materials Pub Date : 2024-06-17 DOI:10.1016/j.dental.2024.05.026

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引用次数: 0

Abstract

Objectives

Baghdadite (Ca₃ZrSi₂O₉) cements of various composition have been investigated in this study regarding an application as endodontic filling materials.

Methods

Cements were either obtained by mixing mechanically activated baghdadite powder with water (maBag) or by subsequently substituting the ß-tricalcium phosphate (ß-TCP) component in a brushite forming calcium phosphate cement. The cements were analyzed for their mechanical performance, injectability, radiopacity, phase composition and antimicrobial properties.

Results

The cements demonstrated sufficient mechanical performance with a compressive strength of ∼1 MPa (maBag) and 2.3 – 17.4 MPa (substituted calcium phosphate cement), good injectability > 80 % depending on the powder to liquid ratio and an intrinsic radiopacity of 1.13 – 2.05 mm aluminum equivalent. Immersion in artificial saliva proved their bioactivity by the formation of calcium phosphate and calcium silicate precipitates on the cement surface. The bacterial activity of Staphylococcus aureus cultured on the surface of the cements was found to be similar compared to clinical standard ProRoot MTA cement or even reduced by a factor of 3 for Streptococcus mutans.

Significance

In combination with their antibacterial properties, baghdadite cements are thought to have the potential to fulfil the clinical requirements for endodontic filling materials.

查看原文本刊更多论文

评估 Baghdadite（Ca3ZrSi2O9）水门汀作为新型牙髓充填材料的应用。

目的本研究对不同成分的巴氏合金（Ca3ZrSi2O9）水门汀作为牙髓充填材料的应用进行了调查：方法：通过将机械活化的巴格达岩粉末与水混合（maBag）或在刷状磷酸钙水门汀中替代ß-磷酸三钙（ß-TCP）成分来获得水门汀。对这些水门汀的机械性能、可注射性、放射性、相组成和抗菌性能进行了分析：结果：水门汀具有足够的机械性能，抗压强度为 1 兆帕（maBag）和 2.3 - 17.4 兆帕（替代磷酸钙水门汀），良好的可注射性大于 80%（取决于粉末与液体的比例），固有的不透射线性为 1.13 - 2.05 毫米铝当量。通过在水门汀表面形成磷酸钙和硅酸钙沉淀，在人工唾液中的浸泡证明了它们的生物活性。在水门汀表面培养的金黄色葡萄球菌的细菌活性与临床标准的 ProRoot MTA 水门汀相似，甚至对变异链球菌的活性降低了 3 倍：意义：结合其抗菌特性，巴格达岩水门汀被认为有可能满足牙髓充填材料的临床要求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dental Materials 工程技术-材料科学：生物材料

CiteScore

9.80

自引率

10.00%

发文量

290

审稿时长

67 days

期刊介绍： Dental Materials publishes original research, review articles, and short communications. Academy of Dental Materials members click here to register for free access to Dental Materials online. The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology. Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.