The Effect of Topical Rosa damascena Mill. and Sesamum indicum L. Oils on the Avoidance of Striae Gravidarum: A Randomised Controlled Trial

IF 2.2 4区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE
F. Mirzaei , K. Vakilian , S. Asnaashari , A. Ostadrahimi , K. Ghahremanzadeh , A. Farshbaf-Khalili
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Abstract

Introduction

Striae gravidarum (SG) is the most prevalent physiological skin change experienced by pregnant women during gestation. This study aimed to evaluate the effects of topical Sesamum indicum L. (Sesame) and Rosa damascena Mill. (R damascena) oils because of their skin-healing properties in preventing SG in nulliparous females.

Methods

This study was a triple-blinded, randomised, controlled trial conducted on 150 nulliparous mothers in the age group of 18–35 from 16 to 20 weeks of pregnancy. Participants were randomly assigned to the R damascena oil, Sesame oil, or placebo group with a 1:1:1 randomisation ratio. They received the allocated intervention of 1 g, twice/d, without massaging the abdomen for 20 weeks. Socio-demographic and obstetric characteristics and SG risk factors were completed at baseline. Davey's and Kamini's methods were used as data-gathering tools for assessing striae and itching.

Results

There were no significant differences between study groups in baseline characteristics. The occurrence of striae between 35 and 38 weeks of pregnancy was similar (72%, 74%, and 74% among R damascena oil, Sesame oil, and the placebo group, respectively; P = 0.919). More than 50% of participants had severe SG. The itching was reported by 40%, 54%, and 40% of participants among the R damascena oil, Sesame oil, and control groups, respectively (P = 0.129), which was mild mostly. Skin redness and itching following topical oil use were the reported side effects.

Conclusions

This study indicated that using R damascene and Sesame oil 10% did not affect the incidence and severity of striae and itching compared to the control.

局部使用大马士革蔷薇和印度芝麻油对避免妊娠纹的影响:随机对照试验
引言 妊娠纹(SG)是孕妇在妊娠期间最常见的皮肤生理变化。本研究旨在评估外用 Sesamum indicum L.(芝麻)和 Rosa damascena Mill.(本研究是一项三重盲法随机对照试验,对象是 150 名年龄介于 18-35 岁之间、怀孕 16-20 周的单胎母亲。参与者按 1:1:1 的随机分配比例被随机分配到大马士革籽油组、芝麻油组或安慰剂组。在 20 周的时间里,他们每天两次,每次 1 克,在不按摩腹部的情况下接受所分配的干预。基线调查包括社会人口学特征、产科特征和 SG 风险因素。戴维法和卡米妮法被用作评估条纹和瘙痒的数据收集工具。妊娠 35 至 38 周间条纹的发生率相似(大马士革油组、芝麻油组和安慰剂组分别为 72%、74% 和 74%;P = 0.919)。50%以上的参与者有严重的 SG。大马士革籽油组、芝麻油组和对照组中分别有 40%、54% 和 40% 的参与者报告有瘙痒症状(P = 0.129),大部分为轻度瘙痒。结论 本研究表明,与对照组相比,使用 10%的大马士革树脂油和芝麻油不会影响条纹和瘙痒的发生率和严重程度。
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来源期刊
Journal of Herbal Medicine
Journal of Herbal Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.90
自引率
0.00%
发文量
94
期刊介绍: The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.
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