Probiotic Interventions for Polycystic Ovarian Syndrome – A Comprehensive Review

Abstract

Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by hormonal dysregulation, metabolic disturbances, and reproductive abnormalities. Probiotics are the gut bacteria which helps in digestion and possess several functionalities positively in body like immunomodulation, hormonal balancing, antihypertensive etc. There are evidences pointing for preventive as well as therapeutic results from the PCOS symptoms by administrating probiotics to the adolescent women. Some triggers causing implications of gut microbiota alterations in PCOS, including modulation of host metabolism, inflammation, insulin resistance, and reproductive function. Present paper reviews the mechanism through which these outcomes are achieved.