Eleutherococcus giraldii (Harms) Nakai: a review of botany, traditional uses, phytochemistry, pharmacology and quality control

IF 7.3 2区 生物学 Q1 PLANT SCIENCES
Ling Li, Jie Zhang, Li-wen Zhong, Rui Gu, Shi-hong Zhong
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Abstract

Eleutherococcus giraldii (Harms) Nakai (EG, thereafter) is a perennial shrub, widely recognized for its medicinal properties. The stem bark of this plant is a widely used traditional Chinese herb with the effects of dispelling dampness, strengthening sinews and invigorating bones. Native to the upper reaches of the Minjiang River, EG is a prevalent Qiang medicine. It was included in the 2010 Edition of the Standard of Traditional Chinese Medicines of Sichuan Province. In the 1990s, numerous phytochemistry was carried out. Several chemical constituents have been identified, including saponins, lignans, alkali nucleosides, polysaccharides, alkanes, organic acids, and other compounds. Notably, glycosides and their glycosides with ivy saponins as ligands stand out among these constituents. Modern pharmacological studies have shown that the stem bark of Eleutherococcus giraldii (Harms) Nakai (EGSB, thereafter) has anti-inflammatory, immunomodulatory, anti-tumour, anti-oxidant, anti-ischemic and hepatoprotective effects. In addition to its stem bark being used in medicine, the young leaves of EG are the traditional food of the Qiang people, which has been developed into a tea product and pushed to the market. The prospect of industrialisation is good. This comprehensive review aims to explore the taxonomic status, botanical characteristics, traditional applications, phytochemistry, pharmacology, and quality control of EG. The primary focus is placed on phytochemical and pharmacological investigations.

Graphical abstract

Abstract Image

Abstract Image

Eleutherococcus giraldii (Harms) Nakai:植物学、传统用途、植物化学、药理学和质量控制综述
棘球绦虫(Eleutherococcus giraldii (Harms) Nakai)是一种多年生灌木,因其药用价值而被广泛认可。这种植物的茎皮是一种广泛使用的传统中草药,具有祛湿,强筋,补骨的作用。EG原产于岷江上游,是一种流行的羌药。入选2010年版《四川省中药标准》。在20世纪90年代,进行了大量的植物化学研究。已经鉴定出几种化学成分,包括皂苷、木脂素、碱核苷、多糖、烷烃、有机酸和其他化合物。值得注意的是,在这些成分中,糖苷及其以常春藤皂苷为配体的糖苷脱颖而出。现代药理学研究表明,吉拉尔底棘球蚴(Eleutherococcus giraldii (Harms) Nakai, EGSB,此后)的茎皮具有抗炎、免疫调节、抗肿瘤、抗氧化、抗缺血和保护肝脏的作用。其茎皮除药用外,嫩叶是羌族的传统食品,已被开发成茶叶产品推向市场。工业化的前景是好的。本文就其分类地位、植物特性、传统应用、植物化学、药理及质量控制等方面进行综述。主要的重点放在植物化学和药理学研究上。图形抽象
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来源期刊
Phytochemistry Reviews
Phytochemistry Reviews PLANT SCIENCES-
CiteScore
16.30
自引率
2.60%
发文量
54
审稿时长
2 months
期刊介绍: Phytochemistry Reviews is the sole review journal encompassing all facets of phytochemistry. It publishes peer-reviewed papers in six issues annually, including topical issues often stemming from meetings organized by the Phytochemical Society of Europe. Additionally, the journal welcomes original review papers that contribute to advancing knowledge in various aspects of plant chemistry, function, biosynthesis, effects on plant and animal physiology, pathology, and their application in agriculture and industry. Invited meeting papers are supplemented with additional review papers, providing a comprehensive overview of the current status across all areas of phytochemistry.
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