Management strategy of a periodontist in treating a patient with bisphosphonate-related jaw osteonecrosis: a clinical case

D. D. Teremov, V. A. Rumyantsev
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Abstract

Relevance. Drug-related osteonecrosis of the jaws is a serious complication of antiresorptive therapy in patients with cancer, systemic osteoporosis, and Paget's disease, significantly impacting the patients' quality of life.Clinical case description. This article analyzes the progressive oral manifestations of a complication of antiresorptive therapy—drug-related osteonecrosis of the jaws—in a patient with breast cancer. The osteonecrosis was characterized by an exposed bone area in the upper jaw, periodontal inflammation, and a malodorous discharge from the mouth. The paper details the appropriate management strategy by the periodontist, tailored to the patient's individual characteristics.Conclusion. Early initiation of a conservative, comprehensive, and gentle treatment regimen can reduce inflammation in periodontal tissues, including the necrotic area, thus avoiding the need for high-risk surgical procedures.
牙周病医生治疗双膦酸盐相关颌骨骨坏死患者的管理策略:一个临床病例
相关性。药物相关性颌骨坏死是癌症、全身性骨质疏松症和帕吉特氏病患者抗骨质吸收治疗的一种严重并发症,严重影响患者的生活质量。本文分析了一名乳腺癌患者在接受抗骨质吸收治疗后出现的并发症--药物性颌骨坏死的进行性口腔表现。骨坏死的特征是上颌骨外露、牙周炎症和口腔恶臭分泌物。本文详细介绍了牙周病医生根据患者的个体特征采取的适当治疗策略。结论:及早采取保守、全面、温和的治疗方案可以减轻牙周组织(包括坏死区)的炎症,从而避免高风险的外科手术。
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