A speech therapy treatment protocol for exercise induced laryngeal obstruction

Tom Karlsen, Kristine Vreim, O. Røksund, M. Vollsæter, P. Muralitharan, Thor-Andre Ellingsen, J. Heimdal, T. Halvorsen, H. Clemm
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Abstract

Exercise induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, relevant to 5%–7% of young people. It is caused by paradoxical inspiratory adduction of laryngeal structures and diagnosed by continuous visualization of the larynx during high intensity exercise. Empirical data suggest that EILO consists of different subtypes that require different therapeutic approaches. Currently applied treatment approaches do not rest on randomized controlled trials (RCTs), and thus evidence-based guidelines cannot be established. This protocol describes the speech therapy treatment approach which is applied to EILO patients in a large prospective RCT called HelpILO.Consenting patients consecutively diagnosed with EILO at Haukeland University Hospital are randomized into four treatment arms. Speech therapy is represented in two of these, provided in a structured manner based on general speech therapy principles and abdominal breathing, combined with experience obtained with these patients at our hospital during the last decades. The main outcome measure of HelpILO is changes of laryngoscopically visualized laryngeal adduction, rated at peak exercise before vs. after interventions, using a validated scoring system.Despite widespread use of speech therapy in patients with EILO, this approach is insufficiently tested in RCTs, and the study is therefore considered ethically appropriate. The study will provide knowledge listed as a priority in a recent statement issued by major respiratory and laryngological societies and requested by clinicians and researchers engaged in this area. The results will be presented at relevant conferences, patient fora, and media platforms, and published in relevant peer reviewed international journals.
运动诱发喉阻塞的语言治疗方案
运动诱发喉阻塞(EILO)是年轻人出现用力呼吸问题的常见原因,与 5%-7%的年轻人有关。它是由喉部结构的矛盾性吸气内收引起的,可通过在高强度运动时持续观察喉部来诊断。经验数据表明,EILO 包括不同的亚型,需要不同的治疗方法。目前采用的治疗方法并不基于随机对照试验(RCT),因此无法制定循证指南。本方案介绍了在一项名为 "HelpILO "的大型前瞻性随机对照试验中应用于 EILO 患者的言语治疗方法。其中两个治疗组以语言治疗为代表,根据一般语言治疗原则和腹式呼吸法,结合本医院在过去几十年中对这些患者的治疗经验,以结构化的方式提供治疗。HelpILO 的主要结果测量指标是喉镜观察到的喉头内收的变化,在干预前和干预后的运动高峰期,使用经过验证的评分系统进行评分。尽管言语治疗在 EILO 患者中得到了广泛应用,但这种方法在 RCT 中没有得到充分验证,因此这项研究被认为是符合伦理要求的。这项研究将提供主要呼吸和喉科学会最近发表的一份声明中列为优先事项的知识,该领域的临床医生和研究人员也要求获得这些知识。研究结果将在相关会议、患者论坛和媒体平台上公布,并在相关的同行评审国际期刊上发表。
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