Persistent headache and chronic daily headache after COVID-19: a prospective cohort study.

IF 3.4 3区 医学 Q2 CLINICAL NEUROLOGY
Larissa Clementino Leite Sá Carvalho, Priscila Aparecida da Silva, Pedro Augusto Sampaio Rocha-Filho
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引用次数: 0

Abstract

Background: Little is known about the frequency and impact of the persistent headache and about the incidence of chronic daily headache (CDH) after coronavirus disease 2019 (COVID-19). The aim of this prospective cohort study was to assess the incidence, risk factors, characteristics, and impact of CDH in patients with COVID-19.

Methods: In the first stage, 288 patients were interviewed by telephone after the acute phase of COVID-19. Subsequently, 199 patients who presented headache were reinterviewed at least one year after COVID-19. Headaches that persisted beyond the acute phase of COVID-19 for three or more months and presented frequency ≥ 45 days over the first three months were considered to be CDH.

Results: One hundred and twenty-three patients were included, 56% were females; median age: 50 years (25th and 75th percentile: 41;58). The headache persisted beyond the acute phase of COVID-19 in 52%, and 20.3% had CDH (95% confidence interval: 13.6-28.2). Individuals who previously had headaches and who had headaches of greater intensity during the acute phase were at higher risk of developing CDH. The group with CDH included more females, greater impact of headache, more persistence of headache beyond the 120th day of COVID-19 and less throbbing headache than did the other individuals whose headache persisted.

Conclusions: Patients who had COVID-19 had a high incidence of CDH. Previous headache and greater intensity of headache were associated with higher risk of CDH.

COVID-19 后的持续性头痛和慢性日常头痛:一项前瞻性队列研究。
背景:人们对2019年冠状病毒病(COVID-19)后持续性头痛的频率和影响以及慢性每日头痛(CDH)的发病率知之甚少。这项前瞻性队列研究旨在评估 COVID-19 患者 CDH 的发病率、风险因素、特征和影响:第一阶段,在 COVID-19 急性期结束后,对 288 名患者进行了电话访谈。随后,在 COVID-19 至少一年后对 199 名出现头痛的患者进行了再次访谈。头痛持续时间超过 COVID-19 急性期三个月或三个月以上,且在前三个月中头痛频率≥ 45 天的患者被视为 CDH:共纳入 123 名患者,其中女性占 56%;年龄中位数为 50 岁(第 25 百分位数和第 75 百分位数分别为 41 岁和 58 岁)。52%的患者头痛持续时间超过了 COVID-19 的急性期,20.3%的患者为 CDH(95% 置信区间:13.6-28.2)。曾有过头痛且在急性期头痛程度较重的人患 CDH 的风险较高。与其他头痛持续存在的患者相比,CDH患者中女性更多,头痛的影响更大,头痛持续时间超过COVID-19的第120天,搏动性头痛更少:结论:COVID-19患者的CDH发病率较高。结论:COVID-19 患者的 CDH 发生率较高,曾患头痛和头痛强度较大的患者患 CDH 的风险较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Korean Journal of Pain
Korean Journal of Pain Medicine-Anesthesiology and Pain Medicine
CiteScore
5.40
自引率
7.10%
发文量
57
审稿时长
16 weeks
期刊介绍: Korean Journal of Pain (Korean J Pain, KJP) is the official journal of the Korean Pain Society, founded in 1986. It has been published since 1988. It publishes peer reviewed original articles related to all aspects of pain, including clinical and basic research, patient care, education, and health policy. It has been published quarterly in English since 2009 (on the first day of January, April, July, and October). In addition, it has also become the official journal of the International Spinal Pain Society since 2016. The mission of the Journal is to improve the care of patients in pain by providing a forum for clinical researchers, basic scientists, clinicians, and other health professionals. The circulation number per issue is 50.
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