Assessing Correlations and Demographic Interactions Between PROMIS25 and SRS30 in Pediatric Patients With Spinal Deformity.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-06-17 DOI:10.1097/BPO.0000000000002756

Kian Niknam, Justin T Less, Ishaan Swarup

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引用次数: 0

Abstract

Introduction: Historically, patient-reported outcome measures (PROMs) have been measured using anatomy-specific instruments. However, these instruments may be influenced by the presence of concomitant illnesses not associated with the orthopaedic condition. As such, standardized PROM tool, such as PROMIS25, have been developed to assess patient outcomes. In this study, we aim to compare the correlation and association between 2 common PROMs used for pediatric patients with spinal deformity.

Methods: This study included patients younger than 21 years who were indicated for spinal deformity surgery at our institution. All patients were invited to complete SRS-30 and PROMIS-25 instruments through an automated, electronic patient-reported outcome platform before surgery. Patient demographics were recorded and Spearman correlations were calculated between the various PROMIS and SRS domains. Correlations were compared between different baseline characteristics and demographics using a rho-to-z transformation method. Ceiling and floor effects were also investigated.

Results: A total of 207 patients were enrolled in this study. The majority of PROMIS and SRS domains had moderate to strong correlations, with higher correlations observed when each instrument tried to capture the same construct. For example, there was strong correlation between PROMIS raw pain and SRS pain (ρ=-0.86, P <0.01), and PROMIS Depression and SRS Mental Health (ρ=-0.76, P <0.01). Ceiling effects ranged from 1.0 to 16.9% in SRS and 0.5 to 28.5% is PROMIS. Floor effects ranged from 0.5 to 1.5% in SRS and 0.5 to 29.0% in PROMIS. There were significant differences in the correlation between SRS Mental Health and PROMIS Depression when comparing between different sexes (male: ρ=-0.74, female: ρ=-0.59, P =0.04). In addition, there were significant differences in the correlation between SRS Mental Health and PROMIS Anxiety when comparing between different insurance payors (commercial: ρ=-0.86, female: ρ=-0.75, P =0.03).

Conclusions: There is strong correlation between SRS and PROMIS domains in pediatric patients with spinal deformity. These correlations can differ by baseline characteristics and demographics. Providers should consider these differences when interpreting PROMs in diverse patient populations.

Level of evidence: Level III; Retrospective comparative study.

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评估小儿脊柱畸形患者 PROMIS25 和 SRS30 之间的相关性和人口统计学交互作用。

介绍：一直以来，患者报告的结果测量（PROMs）都是使用特定的解剖工具来测量的。然而，这些工具可能会受到与骨科疾病无关的伴随疾病的影响。因此，人们开发了标准化的 PROM 工具（如 PROMIS25）来评估患者的治疗效果。在本研究中，我们旨在比较脊柱畸形儿科患者常用的两种 PROM 之间的相关性和关联性：本研究纳入了本院 21 岁以下有脊柱畸形手术指征的患者。所有患者均被邀请在手术前通过自动电子患者报告结果平台完成 SRS-30 和 PROMIS-25 工具。我们记录了患者的人口统计学特征，并计算了 PROMIS 和 SRS 各领域之间的斯皮尔曼相关性。使用rho-to-z转换方法比较了不同基线特征和人口统计学之间的相关性。此外，还研究了上限和下限效应：本研究共招募了 207 名患者。PROMIS和SRS的大部分领域具有中等至较强的相关性，当两种工具试图捕捉相同的结构时，相关性更高。例如，PROMIS 原始疼痛与 SRS 疼痛之间存在很强的相关性（ρ=-0.86，PC 结论：脊柱畸形儿科患者的 SRS 和 PROMIS 领域之间存在很强的相关性。这些相关性会因基线特征和人口统计学特征的不同而有所差异。医疗服务提供者在解释不同患者群体的 PROMs 时应考虑这些差异：证据级别：III级；回顾性比较研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.