Parasite infection in a cell population: role of the partitioning kernel.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Aline Marguet, Charline Smadi
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引用次数: 0

Abstract

We consider a cell population subject to a parasite infection. Cells divide at a constant rate and, at division, share the parasites they contain between their two daughter cells. The sharing may be asymmetric, and its law may depend on the number of parasites in the mother. Cells die at a rate which may depend on the number of parasites they carry, and are also killed when this number explodes. We study the survival of the cell population as well as the mean number of parasites in the cells, and focus on the role of the parasites partitioning kernel at division.

Abstract Image

细胞群中的寄生虫感染:分割核的作用。
我们考虑一个受到寄生虫感染的细胞群。细胞以恒定的速度分裂,在分裂过程中,它们所含的寄生虫在两个子细胞之间共享。这种分享可能是不对称的,其规律可能取决于母细胞中的寄生虫数量。细胞的死亡速度可能取决于其携带的寄生虫数量,当寄生虫数量激增时,细胞也会死亡。我们研究了细胞群的存活率以及细胞中寄生虫的平均数量,并重点研究了分裂时寄生虫分割内核的作用。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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