Application of the 2016 ASE-EACVI Criteria for the Assessment of Diastolic Function in Arterial Hypertension.

IF 3.1 Q2 PERIPHERAL VASCULAR DISEASE

High Blood Pressure & Cardiovascular Prevention Pub Date : 2024-07-01 Epub Date: 2024-06-15 DOI:10.1007/s40292-024-00655-z

Grazia Canciello, Raffaele Izzo, Eduardo Bossone, Raffaele Piccolo, Daniela Pacella, Francesco Ferrara, Maria Lembo, Maria-Virginia Manzi, Andreina Carbone, Costantino Mancusi, Fiorenzo Simonetti, Giuseppe Giugliano, Carmine Morisco, Antonio Cittadini, Giovanni Esposito, Maria-Angela Losi

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引用次数: 0

Abstract

Introduction: No data are available on the diagnostic algorithms recommended by guidelines for the assessment of diastolic dysfunction (DD) in patients with arterial hypertension.

Aim: To fill this gap, we evaluated diastolic function in hypertensive patients with and without LVH matched with healthy subjects by applying 2016 American Society of Echocardiography-European Association of Cardiovascular Imaging Guidelines for the evaluation of LV diastolic function.

Methods: 717 healthy and hypertensives with normal LV ejection fraction and with and without LV hypertrophy (LVH), matched 1:1:1 from two prospective registries, represented the study population.

Results: By applying algorithm A, indeterminate pattern was found in 0.4% of healthy, in 6.3% of hypertensives without LVH, and in 21% with LVH (overall p < 0.05 vs. healthy). DD was absent in healthy, however present in 2 and 8% of hypertensives without and with LVH (p = 0.06 and p = 0.001 vs. healthy, respectively). By applying algorithm B, no cases of indeterminate pattern were found. DD was observed in 2.9% of healthy, 7 and 10.5% of hypertensives without and with LVH (p < 0.05 vs. healthy).

Conclusions: The use of algorithm A should be limited only to truly normal subjects, whereas algorithm B should be applied to all patients with hypertension, even without comorbidities and irrespective of LVH.

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应用 2016 ASE-EACVI 标准评估动脉高血压的舒张功能。

导言：目的：为了填补这一空白，我们采用2016年美国超声心动图学会-欧洲心血管成像协会左心室舒张功能评估指南，评估了与健康受试者相匹配的有左心室肥厚和无左心室肥厚的高血压患者的舒张功能。方法：研究对象包括717名健康人和左心室射血分数正常的高血压患者，以及左心室肥厚（LVH）患者和无左心室肥厚（LVH）患者，他们来自两个前瞻性登记处，配对比例为1:1:1：通过应用算法 A，在 0.4% 的健康人、6.3% 的无左心室肥厚的高血压患者和 21% 的左心室肥厚患者中发现了不确定模式（总体 p 结论：使用算法 A 时，应考虑左心室射血分数正常、有左心室肥厚和无左心室肥厚的人群：算法 A 的使用应仅限于真正正常的受试者，而算法 B 则应适用于所有高血压患者，即使没有合并症，也不论有无左心室功能不全。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

High Blood Pressure & Cardiovascular Prevention PERIPHERAL VASCULAR DISEASE-

CiteScore

5.70

自引率

3.30%

发文量

期刊介绍： High Blood Pressure & Cardiovascular Prevention promotes knowledge, update and discussion in the field of hypertension and cardiovascular disease prevention, by providing a regular programme of independent review articles covering key aspects of the management of hypertension and cardiovascular diseases. The journal includes: Invited ''State of the Art'' reviews. Expert commentaries on guidelines, major trials, technical advances.Presentation of new intervention trials design.''Pros and Cons'' or round tables on controversial issues.Statements on guidelines from hypertension and cardiovascular scientific societies.Socio-economic issues.Cost/benefit in prevention of cardiovascular diseases.Monitoring of healthcare systems.News and views from the Italian Society of Hypertension (including abstracts).All manuscripts are subject to peer review by international experts. Letters to the editor are welcomed and will be considered for publication.