Recent Advancements in the Analyses of Natural Products.

IF 1.6 4区 医学 Q4 BIOCHEMICAL RESEARCH METHODS
Sinem Aslan Erdem, Aysegul Dogan, Sevinc Kurbanoglu
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Abstract

Since ancient times, medicinal plants and their active ingredients have played a key role in treating a wide array of ailments. Notably, in recent years, there has been a burgeoning interest in treatments using products derived from natural sources, and some have been studied as clinical treatments for a variety of disorders. The use of natural products to treat illness has gained increasing scientific and public interest. Not only to ensure quality control but also to verify their efficacy as active ingredients in various pharmaceutical formulations, the evaluation of natural products is of paramount importance. In this field, analytical methods like spectroscopy, electrophoresis, and chromatography are essential and are constantly being improved upon. Chromatographic techniques are essential for determining the quality and authenticity of natural products. Moreover, strict adherence to internationally recognized norms in validating analytical procedures guarantees the accuracy and dependability of results. Continual research initiatives are essential for tackling issues like adulteration and enhancing customer trust in natural products. This review navigates through the complex field of quality control methodologies and analytical techniques applied in evaluating plant-derived sources, which are generally used as natural products, and focuses on the analysis of Hypericum, Curcuma, and Cannabis species.

天然产品分析的最新进展。
自古以来,药用植物及其活性成分在治疗各种疾病方面发挥着重要作用。值得注意的是,近年来,人们对使用天然产品进行治疗的兴趣日益浓厚,其中一些产品已被研究用于各种疾病的临床治疗。利用天然产品治疗疾病已越来越受到科学界和公众的关注。不仅要确保质量控制,还要验证天然产品作为各种药物配方中活性成分的功效,因此对天然产品进行评估至关重要。在这一领域,光谱法、电泳法和色谱法等分析方法至关重要,并在不断改进。色谱技术对于确定天然产品的质量和真实性至关重要。此外,在验证分析程序时严格遵守国际公认的规范可确保结果的准确性和可靠性。要解决掺假等问题并提高客户对天然产品的信任度,持续的研究举措必不可少。本综述介绍了质量控制方法和分析技术的复杂领域,这些方法和技术适用于评估通常用作天然产品的植物来源,并重点分析了金丝桃、莪术和大麻物种。
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来源期刊
CiteScore
3.10
自引率
5.60%
发文量
327
审稿时长
7.5 months
期刊介绍: Combinatorial Chemistry & High Throughput Screening (CCHTS) publishes full length original research articles and reviews/mini-reviews dealing with various topics related to chemical biology (High Throughput Screening, Combinatorial Chemistry, Chemoinformatics, Laboratory Automation and Compound management) in advancing drug discovery research. Original research articles and reviews in the following areas are of special interest to the readers of this journal: Target identification and validation Assay design, development, miniaturization and comparison High throughput/high content/in silico screening and associated technologies Label-free detection technologies and applications Stem cell technologies Biomarkers ADMET/PK/PD methodologies and screening Probe discovery and development, hit to lead optimization Combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) Chemical library design and chemical diversity Chemo/bio-informatics, data mining Compound management Pharmacognosy Natural Products Research (Chemistry, Biology and Pharmacology of Natural Products) Natural Product Analytical Studies Bipharmaceutical studies of Natural products Drug repurposing Data management and statistical analysis Laboratory automation, robotics, microfluidics, signal detection technologies Current & Future Institutional Research Profile Technology transfer, legal and licensing issues Patents.
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