A new method for identification of traditional Chinese medicine constitution based on tongue features with machine learning.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Mei Zhao, Hengyu Zhou, Jing Wang, Yongyue Liu, Xiaoqing Zhang
{"title":"A new method for identification of traditional Chinese medicine constitution based on tongue features with machine learning.","authors":"Mei Zhao, Hengyu Zhou, Jing Wang, Yongyue Liu, Xiaoqing Zhang","doi":"10.3233/THC-240128","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The theory of Chinese medicine (TCM) constitution contributes to the optimisation of individualised healthcare programmes. However, at present, TCM constitution identification mainly relies on inefficient questionnaires with subjective bias. Efficient and accurate TCM constitution identification can play an important role in individualised medicine and healthcare.</p><p><strong>Objective: </strong>Building an efficient model for identifying traditional Chinese medicine constitutions using objective tongue features and machine learning techniques.</p><p><strong>Methods: </strong>The DS01-A device was applied to collect tongue images and extract features. We trained and evaluated five machine learning models: Support Vector Machine (SVM), Decision Tree (DT), Random Forest (RF), LightGBM (LGBM), and CatBoost (CB). Among these, we selected the model with the best performance as the base classifier for constructing our heterogeneous ensemble learning model. Using various performance metrics, including classification accuracy, precision, recall, F1 score, and area under curve (AUC), to comprehensively evaluate model performance.</p><p><strong>Results: </strong>A total of 1149 tongue images were obtained and 45 features were extracted, forming dataset 1. RF, LGBM, and CB were selected as the base learners for the RLC-Stacking. On dataset 1, RLC-Stacking1 achieved an accuracy of 0.8122, outperforming individual classifiers. After feature selection, the classification accuracy of RLC-Stacking2 improved to 0.8287, an improvement of 0.00165 compared to RLC-Stacking1. RLC-Stacking2 achieved an accuracy exceeding 0.85 for identifying each TCM constitution type, indicating excellent identification performance.</p><p><strong>Conclusion: </strong>The study provides a reliable method for the accurate and rapid identification of TCM constitutions and can assist clinicians in tailoring individualized medical treatments based on personal constitution types and guide daily health care. The information extracted from tongue images serves as an effective marker for objective TCM constitution identification.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3233/THC-240128","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: The theory of Chinese medicine (TCM) constitution contributes to the optimisation of individualised healthcare programmes. However, at present, TCM constitution identification mainly relies on inefficient questionnaires with subjective bias. Efficient and accurate TCM constitution identification can play an important role in individualised medicine and healthcare.

Objective: Building an efficient model for identifying traditional Chinese medicine constitutions using objective tongue features and machine learning techniques.

Methods: The DS01-A device was applied to collect tongue images and extract features. We trained and evaluated five machine learning models: Support Vector Machine (SVM), Decision Tree (DT), Random Forest (RF), LightGBM (LGBM), and CatBoost (CB). Among these, we selected the model with the best performance as the base classifier for constructing our heterogeneous ensemble learning model. Using various performance metrics, including classification accuracy, precision, recall, F1 score, and area under curve (AUC), to comprehensively evaluate model performance.

Results: A total of 1149 tongue images were obtained and 45 features were extracted, forming dataset 1. RF, LGBM, and CB were selected as the base learners for the RLC-Stacking. On dataset 1, RLC-Stacking1 achieved an accuracy of 0.8122, outperforming individual classifiers. After feature selection, the classification accuracy of RLC-Stacking2 improved to 0.8287, an improvement of 0.00165 compared to RLC-Stacking1. RLC-Stacking2 achieved an accuracy exceeding 0.85 for identifying each TCM constitution type, indicating excellent identification performance.

Conclusion: The study provides a reliable method for the accurate and rapid identification of TCM constitutions and can assist clinicians in tailoring individualized medical treatments based on personal constitution types and guide daily health care. The information extracted from tongue images serves as an effective marker for objective TCM constitution identification.

基于舌头特征的机器学习中药体质辨识新方法。
背景:中医体质理论有助于优化个性化保健方案。然而,目前中医体质辨识主要依靠主观偏差的低效问卷。高效、准确的中医体质辨识可在个体化医疗保健中发挥重要作用:利用客观舌象特征和机器学习技术建立高效的中医体质辨识模型:方法:使用 DS01-A 设备采集舌头图像并提取特征。我们训练并评估了五个机器学习模型:支持向量机 (SVM)、决策树 (DT)、随机森林 (RF)、LightGBM (LGBM) 和 CatBoost (CB)。在这些模型中,我们选择了性能最好的模型作为构建异构集合学习模型的基础分类器。使用各种性能指标,包括分类准确率、精确度、召回率、F1 分数和曲线下面积(AUC),来综合评估模型的性能:共获得 1149 张舌头图像,提取 45 个特征,形成数据集 1。RF、LGBM 和 CB 被选为 RLC-Stacking 的基础学习器。在数据集 1 上,RLC-Stacking1 的准确率达到了 0.8122,优于单个分类器。经过特征选择后,RLC-Stacking2 的分类准确率提高到 0.8287,比 RLC-Stacking1 提高了 0.00165。RLC-Stacking2 对每种中医体质类型的识别准确率都超过了 0.85,显示了出色的识别性能:结论:该研究为准确、快速识别中医体质提供了可靠的方法,可帮助临床医生根据个人体质类型进行个体化治疗,并指导日常保健。从舌苔图像中提取的信息可作为客观中医体质辨识的有效标记。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信