Nicholas Averell, Brandon Goodwin, Seungkyu Park, Seth Spicer, Margaret Wilson, Jessica Mitchell, Nichole Martinez, Meejan Palhang, Jaimy Jabon, Richard Jermyn
{"title":"The concentration of platelets in PRP does not affect pain outcomes in lateral epicondylitis: a systematic review and meta-analysis.","authors":"Nicholas Averell, Brandon Goodwin, Seungkyu Park, Seth Spicer, Margaret Wilson, Jessica Mitchell, Nichole Martinez, Meejan Palhang, Jaimy Jabon, Richard Jermyn","doi":"10.1080/17581869.2024.2360381","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aim:</b> To investigate the analyze the relationship between concentration platelet-dose in platelet-rich plasma (PRP) injections and improvements in pain when treating lateral epicondylitis. <b>Methods:</b> A systematic review was conducted into five medical databases, exploring the difference in pain outcomes based on concentration of PRP. <b>Results:</b> Initial querying of the databases yielded 1408 articles with 20 articles ultimately included. There was no statistical significance between effect sizes of the two treatment groups (high and low platelet concentration; p = 0.976). <b>Conclusion:</b> Both large and small concentrations of platelets depict significant reduction in pain, however, between subgroups there was no significance. It can thus be concluded that concentration of platelets in PRP does not impact overall pain relief.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"223-233"},"PeriodicalIF":1.4000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229443/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pain management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17581869.2024.2360381","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/14 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: To investigate the analyze the relationship between concentration platelet-dose in platelet-rich plasma (PRP) injections and improvements in pain when treating lateral epicondylitis. Methods: A systematic review was conducted into five medical databases, exploring the difference in pain outcomes based on concentration of PRP. Results: Initial querying of the databases yielded 1408 articles with 20 articles ultimately included. There was no statistical significance between effect sizes of the two treatment groups (high and low platelet concentration; p = 0.976). Conclusion: Both large and small concentrations of platelets depict significant reduction in pain, however, between subgroups there was no significance. It can thus be concluded that concentration of platelets in PRP does not impact overall pain relief.
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