The heart rate response to the 6-min walk test in atrial fibrillation patients with or without beta-blockers: Referring to patients with sinus rhythm

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Annals of Noninvasive Electrocardiology Pub Date : 2024-06-14 DOI:10.1111/anec.13128

Feng Xie MD, Zhenzhen Jiang MD, Bo Zhu MD, Juxiang Li MD, PhD, Yanqing Wu MD, PhD, Hai Su MD, PhD

{"title":"The heart rate response to the 6-min walk test in atrial fibrillation patients with or without beta-blockers: Referring to patients with sinus rhythm","authors":"Feng Xie MD, Zhenzhen Jiang MD, Bo Zhu MD, Juxiang Li MD, PhD, Yanqing Wu MD, PhD, Hai Su MD, PhD","doi":"10.1111/anec.13128","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>The aim was to evaluate the effect of beta-blockers (BB) on the response of heart rate (HR) to 6-min walk test (6MWT) in atrial fibrillation (AF) and whether the AF patients treated with BB have a similar HR response to 6MWT as the AF and sinus rhythm (SR) patients without BB treatment at the same resting HR level.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>The before–after study involving 74 AF patients was to evaluate the effect of BB treatment (pre-BB and with BB). The comparison study included 74 BB-treated AF patients (with BB), 74 matched AF patients without BB (no BB), and 74 SR patients. The percentage increase amplitude of HR (HR-PIA) in 6MWT was calculated: [(the exercise HR − the resting HR)/(the resting HR)] × 100%.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The before–after study showed that BB treatment decreased the resting and mean exercise HR (98.6 ± 15.2 vs. 85.5 ± 11.2 bpm and 121.3 ± 17.3 vs. 109.0 ± 16.7 bpm) during 6MWT. The comparison study demonstrated that against the SR, the AF with BB and no BB groups have higher mean exercise HR-PIA (28.2 ± 17.1% and 22.0 ± 9.6%, vs. 6.9 ± 3.7%) when their resting HR is similar. Moreover, the mean exercise HR-PIA was also significantly higher in the with BB group than in the no BB group.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>In AF patients with relatively higher resting HR, BB treatment could decrease the resting and exercise HR during 6MWT. However, BB treatment could not effectively attenuate the exercise HR rise as compared with AF without BB treatment, even with similar resting HR levels.</p>\n </section>\n </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"29 4","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.13128","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Noninvasive Electrocardiology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/anec.13128","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Background

The aim was to evaluate the effect of beta-blockers (BB) on the response of heart rate (HR) to 6-min walk test (6MWT) in atrial fibrillation (AF) and whether the AF patients treated with BB have a similar HR response to 6MWT as the AF and sinus rhythm (SR) patients without BB treatment at the same resting HR level.

Methods

The before–after study involving 74 AF patients was to evaluate the effect of BB treatment (pre-BB and with BB). The comparison study included 74 BB-treated AF patients (with BB), 74 matched AF patients without BB (no BB), and 74 SR patients. The percentage increase amplitude of HR (HR-PIA) in 6MWT was calculated: [(the exercise HR − the resting HR)/(the resting HR)] × 100%.

Results

The before–after study showed that BB treatment decreased the resting and mean exercise HR (98.6 ± 15.2 vs. 85.5 ± 11.2 bpm and 121.3 ± 17.3 vs. 109.0 ± 16.7 bpm) during 6MWT. The comparison study demonstrated that against the SR, the AF with BB and no BB groups have higher mean exercise HR-PIA (28.2 ± 17.1% and 22.0 ± 9.6%, vs. 6.9 ± 3.7%) when their resting HR is similar. Moreover, the mean exercise HR-PIA was also significantly higher in the with BB group than in the no BB group.

Conclusion

In AF patients with relatively higher resting HR, BB treatment could decrease the resting and exercise HR during 6MWT. However, BB treatment could not effectively attenuate the exercise HR rise as compared with AF without BB treatment, even with similar resting HR levels.

Abstract Image

查看原文本刊更多论文

使用或不使用β-受体阻滞剂的心房颤动患者对 6 分钟步行测试的心率反应：参考窦性心律患者。

研究背景目的：评估β-受体阻滞剂（BB）对心房颤动（AF）患者6分钟步行测试（6MWT）心率反应的影响，以及在相同静息心率水平下，接受BB治疗的AF患者与未接受BB治疗的AF和窦性心律（SR）患者对6MWT的心率反应是否相似：74名房颤患者参与的前后对比研究旨在评估BB治疗（BB治疗前和BB治疗后）的效果。对比研究包括 74 名接受 BB 治疗的房颤患者（接受 BB 治疗）、74 名未接受 BB 治疗的匹配房颤患者（未接受 BB 治疗）和 74 名 SR 患者。在 6MWT 中，心率增加幅度的百分比（HR-PIA）是通过计算得出的：[结果：前后对比研究显示，BB治疗降低了6MWT时的静息心率和平均运动心率（98.6 ± 15.2 vs. 85.5 ± 11.2 bpm和121.3 ± 17.3 vs. 109.0 ± 16.7 bpm）。对比研究表明，与SR组相比，有BB房颤组和无BB组在静息心率相似的情况下，平均运动心率-PIA更高（28.2 ± 17.1%和22.0 ± 9.6% vs. 6.9 ± 3.7%）。此外，有BB组的平均运动心率-PIA也明显高于无BB组：结论：对于静息心率相对较高的房颤患者，BB治疗可降低6MWT时的静息和运动心率。结论：对于静息心率相对较高的心房颤动患者，BB 治疗可降低其 6MWT 期间的静息和运动心率，但与未接受 BB 治疗的心房颤动患者相比，即使静息心率水平相似，BB 治疗也不能有效缓解运动心率的上升。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Annals of Noninvasive Electrocardiology 医学-心血管系统

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (A.N.E) is an online only journal that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. ANE is the first journal in an evolving subspecialty that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. The publication includes topics related to 12-lead, exercise and high-resolution electrocardiography, arrhythmias, ischemia, repolarization phenomena, heart rate variability, circadian rhythms, bioengineering technology, signal-averaged ECGs, T-wave alternans and automatic external defibrillation. ANE publishes peer-reviewed articles of interest to clinicians and researchers in the field of noninvasive electrocardiology. Original research, clinical studies, state-of-the-art reviews, case reports, technical notes, and letters to the editors will be published to meet future demands in this field.