Recent Advances in Functional Hydrogels for Treating Dental Hard Tissue and Endodontic Diseases

IF 15.8 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

ACS Nano Pub Date : 2024-06-14 DOI:10.1021/acsnano.4c02754

Huixu Li, Ding Zhang*, Pingping Bao*, Ying Li, Chaoge Liu, Tingting Meng, Chao Wang, Heting Wu* and Keqing Pan*,

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Abstract

Oral health is the basis of human health, and almost everyone has been affected by oral diseases. Among them, endodontic disease is one of the most common oral diseases. Limited by the characteristics of oral biomaterials, clinical methods for endodontic disease treatment still face large challenges in terms of reliability and stability. The hydrogel is a kind of good biomaterial with an adjustable 3D network structure, excellent mechanical properties, and biocompatibility and is widely used in the basic and clinical research of endodontic disease. This Review discusses the recent advances in functional hydrogels for dental hard tissue and endodontic disease treatment. The emphasis is on the working principles and therapeutic effects of treating different diseases with functional hydrogels. Finally, the challenges and opportunities of hydrogels in oral clinical applications are discussed and proposed. Some viewpoints about the possible development direction of functional hydrogels for oral health in the future are also put forward. Through systematic analysis and conclusion of the recent advances in functional hydrogels for dental hard tissue and endodontic disease treatment, this Review may provide significant guidance and inspiration for oral disease and health in the future.

Abstract Image

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治疗牙齿硬组织和牙髓疾病的功能性水凝胶的最新进展。

口腔健康是人类健康的基础，几乎每个人都受到过口腔疾病的影响。其中，牙髓病是最常见的口腔疾病之一。受限于口腔生物材料的特性，临床上治疗牙髓病的方法在可靠性和稳定性方面仍面临较大挑战。水凝胶是一种良好的生物材料，具有可调节的三维网络结构、优异的力学性能和生物相容性，被广泛应用于牙髓病的基础和临床研究。本综述讨论了功能性水凝胶在牙体硬组织和牙髓病治疗方面的最新进展。重点是功能水凝胶治疗不同疾病的工作原理和治疗效果。最后，讨论并提出了水凝胶在口腔临床应用中面临的挑战和机遇。此外，还就功能水凝胶在口腔健康领域未来可能的发展方向提出了一些观点。本综述通过系统分析和总结功能水凝胶在牙体硬组织和牙髓疾病治疗方面的最新进展，可为未来的口腔疾病和健康提供重要的指导和启示。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Nano 工程技术-材料科学：综合

CiteScore

26.00

自引率

4.10%

发文量

1627

审稿时长

1.7 months

期刊介绍： ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.